美洛昔康

Description

Meloxicam · CAS 71125-38-7 · C14H13N3O4S2. UNII VG2QF83CGL. Boiling Point: 581.3±60.0; Melting Point: 256; Melting Point: 254 °C (decomposes).

Identification

CAS Registry Number	71125-38-7
PubChem CID	54677470
Molecular formula	C14H13N3O4S2
IUPAC name	4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1λ6,2-benzothiazine-3-carboxamide
UNII (FDA)	VG2QF83CGL

Computed Descriptors

Molecular Weight	351.4
XLogP3	3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	2
Exact Mass	351.03474825
Monoisotopic Mass	351.03474825
Topological Polar Surface Area	136
Heavy Atom Count	23
Formal Charge	0

Physical & Chemical Properties

Boiling Point	581.3±60.0
Melting Point	256
Melting Point	254 °C (decomposes)
Melting Point	254 °C
Solubility	22
Solubility	1.54e-01 g/L
LogP	0.1
LogP	log Kow = 3.54
LogP	1.9
LogP	2.34

Physical description & handling notes

• Solid
• Crystals from ethylene chloride
• Pastel yellow solid
• Very slightly soluble in methanol. Practically insoluble in water, with higher solubility observed in strong acids and bases.
• 48.7 [ug/mL] (The mean of the results at pH 7.4)
• pKa = 4.08 in water; 4.24 in water/ethanol (1:1); 4.63 in water/ethanol (1:4)

Regulatory Status

GHS notification summary	0.8% (1 / 118)

GHS Hazard Classification

GHS notification summary	0.8% (1 / 118)
Reported hazard statements	H301 (95.8%), H360 (50.8%), H412 (56.8%), H372

Documented Uses

• Nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis, primary dysmenorrhea, fever, and as an analgesic ...
• THERAP CAT (VET): Anti-inflammatory
• Use (kg; approx.) in Germany (2009): >250
• Consumption (g per capita; approx.) in Germany (2009): 0.00305
• Consumption (g per capita) in the USA (2002): 0.00287
• Used to relieve the symptoms of arthritis, primary dysmenorrhea, fever; and as an analgesic, especially where there is an inflammatory component.

Synonyms

meloxicam; 71125-38-7; Mobic; Metacam; Mobicox; Movalis; Movatec; Mobec; Coxicam; Meloxivet; Melfax; UH-AC 62XX; Meloxicamum; Meloxidolor; Meloxoral; Rheumocam

Frequently Asked Questions

What are the CAS number and molecular formula of Meloxicam?

CAS 71125-38-7; molecular formula C14H13N3O4S2; molecular weight — g/mol.

What other names is Meloxicam known by?

meloxicam, 71125-38-7, Mobic, Metacam, Mobicox, Movalis.

Is Meloxicam classified as hazardous?

0.8% of GHS notifications report no hazard classification (1 of 118).

What are the key physical properties of Meloxicam?

Boiling Point: 581.3±60.0; Melting Point: 256; Melting Point: 254 °C (decomposes); Melting Point: 254 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.