SYNEPHRINE

Description

SYNEPHRINE · CAS 94-07-5 · C9H13NO2. UNII PEG5DP7434. LogP: -0.45; Dissociation Constants: 9.6.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• Solid
• 241.8 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID0030588]
• 130.49 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 134.39 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 132 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 134.4 Ų [M+H-H2O]+ [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]

GHS Hazard Classification

Documented Uses

• Synephrine (Class: Other Substances, Added Date: 01-2009)
• Drugs that selectively bind to and activate alpha adrenergic receptors.
• Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
• Drugs used to cause constriction of the blood vessels.
• Drugs designed to treat inflammation of the nasal passages, generally the result of an infection (more often than not the common cold) or an allergy related condition, e.g., hay fever. The inflammation involves swelling of the mucous membrane that lines the nasal passages and results in inordinate mucus production. The primary class of nasal decongestants are vasoconstrictor agents. (From PharmAssist, The Family Guide to Health and Medicine, 1993)
• C01C - Cardiac stimulants excl. cardiac glycosides

Synonyms

Synephrine; Oxedrine; 94-07-5; p-Synephrine; Parasympatol; Analeptin; Simpalon; Sympatol; Synthenate; Sympathol; Ethaphene; DL-SYNEPHRINE; 4-[1-Hydroxy-2-(methylamino)ethyl]phenol; 4-(1-Hydroxy-2-(methylamino)ethyl)phenol; Advantra z; 1-(4-Hydroxyphenyl)-2-methylaminoethanol

Frequently Asked Questions

What are the CAS number and molecular formula of SYNEPHRINE?

CAS 94-07-5; molecular formula C9H13NO2; molecular weight — g/mol.

What other names is SYNEPHRINE known by?

Synephrine, Oxedrine, 94-07-5, p-Synephrine, Parasympatol, Analeptin.

Is SYNEPHRINE classified as hazardous?

Hazard statements reported: H315, H319, H335.

What are the key physical properties of SYNEPHRINE?

LogP: -0.45; Dissociation Constants: 9.6.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.