可的松

Name: 可的松
Brand: 济南圣和化工有限公司

CAS 53-06-5C21H28O5MW 360.4

可的松，CAS 登记号 53-06-5，由济南圣和化工有限公司现货供应，可提供纯度按批次COA提供(不公开发布) 的规格，下游主要用于医药中间体及原料药。支持样品与小批量试用，批量价格请联系我们获取，验收以批次 COA 为准。

规格参数

CAS号53-06-5

分子式C21H28O5

分子量360.4

熔点222 °C

LogP1.47

纯度按批次COA提供(不公开发布)

包装按订单/批次确认(不公开发布)

应用领域医药中间体及原料药

类别医药中间体及原料药

用途与场景

医药中间体及原料药

包装与供货

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

供货周期现货/按订单安排

文件与支持

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常见问题

在哪里能查到可的松的 CAS 号？

本页已列出可的松的 CAS 号：53-06-5，可与随货 COA 核对。

可以提供哪些规格和包装？

常见纯度为按批次COA提供(不公开发布)，包装形式为按订单/批次确认(不公开发布)，特殊规格可在询价时说明。

可的松一般用在什么产品里？

主要涉及医药中间体及原料药。

下单流程是怎样的？

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PubChem 公开数据

Description

Cortisone · CAS 53-06-5 · C21H28O5. UNII V27W9254FZ. Melting Point: 222 °C; Solubility: 0.28 mg/mL at 25 °C; LogP: 1.47.

Identification

CAS Registry Number	53-06-5
PubChem CID	222786
Molecular formula	C21H28O5
IUPAC name	(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione
UNII (FDA)	V27W9254FZ

Computed Descriptors

Molecular Weight	360.4
XLogP3	1.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Exact Mass	360.19367399
Monoisotopic Mass	360.19367399
Topological Polar Surface Area	91.7
Heavy Atom Count	26
Formal Charge	0

Physical & Chemical Properties

Melting Point	222 °C
Solubility	0.28 mg/mL at 25 °C
LogP	1.47
LogP	1.64
Collision Cross Section	191.4 Å² [M-H]-
Collision Cross Section	213.5 Å² [M+Na]+
Collision Cross Section	188.4 Å² [M+H]+

Physical description & handling notes

Solid
257.2 Å² [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID5022857]
180.07 Å² [M-H2O-H]- [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]
188.6 Å² [M+H]+ [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]
172.48 Å² [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
186.07 Å² [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H361 (98%)

H361 (98%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

P203, P280, P318, P405, and P501 (click each P-code to see the statement)

Documented Uses

Pharmaceuticals -> Steroid hormones
Pharmaceuticals -> Animal Drugs -> Approved in Taiwan
Breast Feeding; Lactation; Milk, Human; Corticosteroids, Systemic; Glucocorticoids; Anti-Inflammatory Agents
Cortisone is a known transformation product of Hydrocortisone.
Substances that reduce or suppress INFLAMMATION.
Established Pharmacologic Class [EPC] - Corticosteroid

Synonyms

cortisone; 53-06-5; Kendall's compound E; Reichstein's substance FA; Wintersteiner's compound F; 17-Hydroxy-11-dehydrocorticosterone; 11-Dehydro-17-hydroxycorticosterone; Pregn-4-ene-3,11,20-trione, 17,21-dihydroxy-; Cortisona; Cortisonum; Kortison; 4-Pregnene-17alpha,21-diol-3,11,20-trione; 17alpha,21-Dihydroxypregn-4-ene-3,11,20-trione; DTXSID5022857; Pregn-4-en-17alpha,21-diol-3,11,20-trione; 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione

Frequently Asked Questions

What are the CAS number and molecular formula of Cortisone?

CAS 53-06-5; molecular formula C21H28O5; molecular weight — g/mol.

What other names is Cortisone known by?

cortisone, 53-06-5, Kendall's compound E, Reichstein's substance FA, Wintersteiner's compound F, 17-Hydroxy-11-dehydrocorticosterone.

Is Cortisone classified as hazardous?

Hazard statements reported: H361.

What are the key physical properties of Cortisone?

Melting Point: 222 °C; Solubility: 0.28 mg/mL at 25 °C; LogP: 1.47; LogP: 1.64.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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