2'-deoxyguanosine

Description

2'-deoxyguanosine · CAS 961-07-9 · C10H13N5O4. UNII G9481N71RO. Melting Point: 300 °C; LogP: -1.30; Collision Cross Section: 171.6 Ų [M+K]+.

Identification

CAS Registry Number	961-07-9
PubChem CID	135398592
Molecular formula	C10H13N5O4
IUPAC name	2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
UNII (FDA)	G9481N71RO

Computed Descriptors

Molecular Weight	267.24
XLogP3	-0.9
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	2
Exact Mass	267.09675391
Monoisotopic Mass	267.09675391
Topological Polar Surface Area	135
Heavy Atom Count	19
Formal Charge	0

Physical & Chemical Properties

Melting Point	300 °C
LogP	-1.30
Collision Cross Section	171.6 Ų [M+K]+
Collision Cross Section	159.2 Ų [M-H]-
Collision Cross Section	171.8 Ų [M+Na]+

Physical description & handling notes

• Solid
• 171.7 Ų [M+Na]+ [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]
• 156.76 Ų [M-H]- [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]
• 171.4 Ų [M+K]+ [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]
• 171.7 Ų [M+Na]+ [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]
• 159.1 Ų [M-H]- [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]

Regulatory Status

GHS notification summary	4.7% (2 / 43)

GHS Hazard Classification

GHS notification summary	4.7% (2 / 43)
Reported hazard statements	H302 (93%)

Documented Uses

• Adenine phosphoribosyltransferase deficiency (APRT)
• Adenylosuccinate Lyase Deficiency
• Gout or Kelley-Seegmiller Syndrome
• Mitochondrial DNA depletion syndrome
• Total 17 pathways, visit the HMDB page for details

Synonyms

2'-deoxyguanosine; deoxyguanosine; 961-07-9; Guanosine, 2'-deoxy-; Guanine deoxy nucleoside; CHEBI:17172; DTXSID30883626; G9481N71RO; 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one; NSC-22837; NSC22837; 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one; 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one; 2-amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl)-1H-purin-6-one; 2-amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl)-3H-purin-6-one; 2-amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl)-6,9-dihydro-1H-purin-6-one

Frequently Asked Questions

What are the CAS number and molecular formula of 2'-deoxyguanosine?

CAS 961-07-9; molecular formula C10H13N5O4; molecular weight — g/mol.

What other names is 2'-deoxyguanosine known by?

2'-deoxyguanosine, deoxyguanosine, 961-07-9, Guanosine, 2'-deoxy-, Guanine deoxy nucleoside, CHEBI:17172.

Is 2'-deoxyguanosine classified as hazardous?

4.7% of GHS notifications report no hazard classification (2 of 43).

What are the key physical properties of 2'-deoxyguanosine?

Melting Point: 300 °C; LogP: -1.30; Collision Cross Section: 171.6 Ų [M+K]+; Collision Cross Section: 159.2 Ų [M-H]-.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.