乳果糖

Description

LACTULOSE · CAS 58166-25-9 · C12H22O11. UNII 9XH2P2N8EP. Melting Point: 169; Melting Point: 169 °C; Solubility: 764.0 mg/mL.

Identification

CAS Registry Number	58166-25-9
PubChem CID	11333
Molecular formula	C12H22O11
IUPAC name	(2S,3R,4S,5R,6R)-2-[(2R,3S,4S,5R)-4,5-dihydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
UNII (FDA)	9XH2P2N8EP

Computed Descriptors

Molecular Weight	342.30
XLogP3	-4.3
Hydrogen Bond Donor Count	8
Hydrogen Bond Acceptor Count	11
Rotatable Bond Count	5
Exact Mass	342.11621151
Monoisotopic Mass	342.11621151
Topological Polar Surface Area	190
Heavy Atom Count	23
Formal Charge	0

Physical & Chemical Properties

Melting Point	169
Melting Point	169 °C
Solubility	764.0 mg/mL
LogP	-4.3
Collision Cross Section	179 Ų [M+Na]+
Collision Cross Section	177.7 Ų [M-H]-

Physical description & handling notes

• Solid
• Soluble in cold water, hot water. Solubility in water: 76.4% @ 30 deg. C
• 164.63 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 168.32 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 171.3 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 169.81 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Regulatory Status

Regulatory & Food Contact	CIR / INCI: Cosmetic ingredients (Lactulose) -> CIR (Cosmetic Ingredient Review) CIR / INCI: Humectant; Skin conditioning
GHS notification summary	100% (9 / 9)

GHS Hazard Classification

GHS notification summary	100% (9 / 9)

Documented Uses

• Cosmetics -> Humectant; Skin conditioning
• Breast Feeding; Lactation; Milk, Human; Gastrointestinal Agents; Laxatives
• Medicines for other common symptoms in palliative care
• Oral - Liquid: 3.1 to 3.7 g per 5 mL oral liquid
• Drink plenty of fluids. This drug may cause fluid loss.
• Drugs used for their effects on the gastrointestinal system, as to control gastric acidity, regulate gastrointestinal motility and water flow, and improve digestion.

Synonyms

lactulose; D-Lactulose; 4618-18-2; Bifiteral; Cephulac; Chronulac; Constilac; Lactulosa; Acilac; Cholac; Constulose; Lactulosum; Enulose; Generlac; Heptalac; Laxilose

Frequently Asked Questions

What are the CAS number and molecular formula of LACTULOSE?

CAS 58166-25-9; molecular formula C12H22O11; molecular weight — g/mol.

What other names is LACTULOSE known by?

lactulose, D-Lactulose, 4618-18-2, Bifiteral, Cephulac, Chronulac.

What is the regulatory status of LACTULOSE?

Documented regulatory listings: CIR / INCI: Cosmetic ingredients (Lactulose) -> CIR (Cosmetic Ingredient Review); CIR / INCI: Humectant; Skin conditioning.

Is LACTULOSE classified as hazardous?

100% of GHS notifications report no hazard classification (9 of 9).

What are the key physical properties of LACTULOSE?

Melting Point: 169; Melting Point: 169 °C; Solubility: 764.0 mg/mL; LogP: -4.3.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.