鸟苷水合物

Description

Guanosine · CAS 118-00-3 · C10H13N5O5. UNII 12133JR80S. Melting Point: 239; Melting Point: 239 °C; Solubility: 700.

Identification

CAS Registry Number	118-00-3
PubChem CID	135398635
Molecular formula	C10H13N5O5
IUPAC name	2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
UNII (FDA)	12133JR80S

Computed Descriptors

Molecular Weight	283.24
XLogP3	-1.9
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	2
Exact Mass	283.09166853
Monoisotopic Mass	283.09166853
Topological Polar Surface Area	155
Heavy Atom Count	20
Formal Charge	0

Physical & Chemical Properties

Melting Point	239
Melting Point	239 °C
Solubility	700
Solubility	0.7 mg/mL at 18 °C
LogP	-1.9
LogP	-1.90
LogP	-1.85
Collision Cross Section	175.3 Ų [M+Na]+
Collision Cross Section	163.5 Ų [M+H]+
Collision Cross Section	163 Ų [M-H]-

Physical description & handling notes

• Solid
• 160 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine]
• 174.6 Ų [M+Na]+ [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]
• 174.3 Ų [M+K]+ [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]
• 162.1 Ų [M-H]- [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]
• 174.9 Ų [M+Na]+ [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]

Regulatory Status

Regulatory & Food Contact	CIR / INCI: Opacifying; Skin conditioning
GHS notification summary	11.8% (10 / 85)

GHS Hazard Classification

GHS notification summary	11.8% (10 / 85)
Reported hazard statements	H301 (87.1%)

Documented Uses

• Cosmetics -> Opacifying; Skin conditioning
• Adenine phosphoribosyltransferase deficiency (APRT)
• Adenylosuccinate Lyase Deficiency
• Gout or Kelley-Seegmiller Syndrome
• Mitochondrial DNA depletion syndrome
• Total 17 pathways, visit the HMDB page for details

Synonyms

guanosine; 118-00-3; vernine; guanine riboside; 2-Amino-1,9-dihydro-9-beta-D-ribofuranosyl-6H-purin-6-one; Guanosin; Guanine-9-beta-D-ribofuranoside; 2(3H)-Imino-9-beta-D-ribofuranosyl-9H-purin-6(1H)-one; 9-beta-D-ribofuranosyl-guanine; CHEBI:16750; DTXSID00893055; NSC-19994; 12133JR80S; 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one; 2-AMINO-9-[(2R,3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-6,9-DIHYDRO-1H-PURIN-6-ONE; 2-amino-9-beta-D-ribofuranosyl-1,9-dihydro-6H-purin-6-one

Frequently Asked Questions

What are the CAS number and molecular formula of Guanosine?

CAS 118-00-3; molecular formula C10H13N5O5; molecular weight — g/mol.

What other names is Guanosine known by?

guanosine, 118-00-3, vernine, guanine riboside, 2-Amino-1,9-dihydro-9-beta-D-ribofuranosyl-6H-purin-6-one, Guanosin.

What is the regulatory status of Guanosine?

Documented regulatory listings: CIR / INCI: Opacifying; Skin conditioning.

Is Guanosine classified as hazardous?

11.8% of GHS notifications report no hazard classification (10 of 85).

What are the key physical properties of Guanosine?

Melting Point: 239; Melting Point: 239 °C; Solubility: 700; Solubility: 0.7 mg/mL at 18 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.