奎宁单盐酸盐二水合物

Description

Quinine monohydrochloride dihydrate · CAS 6119-47-7 · C20H24N2O2.ClH. UNII 7CS0WNO31M.

Identification

CAS Registry Number	6119-47-7
PubChem CID	91558
Molecular formula	C20H24N2O2.ClH
IUPAC name	(R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;hydrochloride
UNII (FDA)	7CS0WNO31M
FEMA number	2976

Computed Descriptors

Molecular Weight	360.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	4
Exact Mass	360.1604557
Monoisotopic Mass	360.1604557
Topological Polar Surface Area	45.6
Heavy Atom Count	25
Formal Charge	0
Complexity	457

Regulatory Status

Regulatory & Food Contact	EU Flavoring substances FDA Substance added to food: FLAVORING AGENT OR ADJUVANT Flavoring Agents FLAVOURING_AGENT: Flavouring Agent No safety concern at current levels of intake when used as a flavouring agent Current use levels up to 100 mg/l (as quinine base) in soft drinks not of toxicological concern

GHS Hazard Classification

Reported hazard statements	H302, H312 (91.3%), H332 (91.3%), H317 (66.7%), H334 (44.4%)

Documented Uses

• Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes
• Information on 1 consumer products that contain Quinine hydrochloride in the following categories is provided:
• Cinchonan-9-ol, 6'-methoxy-, hydrochloride (1:1), (8.alpha.,9R)-: ACTIVE
• Cinchonan-9-ol, 6'-methoxy-, hydrochloride (1:?), (8.alpha.,9R)-: INACTIVE
• Agents used in the treatment of malaria. They are usually classified on the basis of their action against plasmodia at different stages in their life cycle in the human. (From AMA, Drug Evaluations Annual, 1992, p1585)
• A subclass of analgesic agents that typically do not bind to OPIOID RECEPTORS and are not addictive. Many non-narcotic analgesics are offered as NONPRESCRIPTION DRUGS.

Synonyms

Quinine hydrochloride; Quinine HCl; Quinine muriate; Quinine monohydrochloride; FEMA No. 2976; Chininum muriaticum; Quinini hydrochloridum; FEMA NO. 2976, DIHYDRATE-; RefChem:930477; 231-437-7; 612-097-2; 711S8Y0T33; Quinine monohydrochloride dihydrate; 130-89-2; Chinimetten; (R)-(6-Methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol hydrochloride

Frequently Asked Questions

What are the CAS number and molecular formula of Quinine monohydrochloride dihydrate?

CAS 6119-47-7; molecular formula C20H24N2O2.ClH; molecular weight — g/mol.

What other names is Quinine monohydrochloride dihydrate known by?

Quinine hydrochloride, Quinine HCl, Quinine muriate, Quinine monohydrochloride, FEMA No. 2976, Chininum muriaticum.

What is the regulatory status of Quinine monohydrochloride dihydrate?

Documented regulatory listings: EU Flavoring substances; FDA Substance added to food: FLAVORING AGENT OR ADJUVANT; Flavoring Agents.

Is Quinine monohydrochloride dihydrate classified as hazardous?

Hazard statements reported: H302, H312, H332, H317, H334.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.