L-MENTHOL

Description

L-MENTHOL · CAS 2216-51-5 · C10H20O. UNII YS08XHA860. Boiling Point: 421 °F at 760 mmHg (NTP, 1992); Boiling Point: 212; Boiling Point: 212 °C.

Identification

CAS Registry Number	2216-51-5
PubChem CID	16666
Molecular formula	C10H20O
IUPAC name	(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexan-1-ol
UNII (FDA)	YS08XHA860
FEMA number	2665
JECFA number	427

Computed Descriptors

Molecular Weight	156.26
XLogP3	3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	1
Exact Mass	156.151415257
Monoisotopic Mass	156.151415257
Topological Polar Surface Area	20.2
Heavy Atom Count	11
Formal Charge	0

Physical & Chemical Properties

Boiling Point	421 °F at 760 mmHg (NTP, 1992)
Boiling Point	212
Boiling Point	212 °C
Boiling Point	212 °C ((-)-isomer 216.5)
Melting Point	100 °F (NTP, 1992)
Melting Point	43
Melting Point	41-43 °C
Melting Point	43 °C
Flash Point	196 °F (NTP, 1992)
Solubility	490

Physical description & handling notes

• D,l-menthol is a white crystalline solid with a peppermint odor and taste. (NTP, 1992)
• Liquid; Other Solid; CBI; Large Crystals
• Other Solid; Liquid
• Solid with an odor of peppermint; [Merck Index] Colorless crystalline solid; [Sigma-Aldrich MSDS]
• Solid
• colourless, hexagonal crystals, usually needle-like; fused masses or crystalline powder with a pleasant, peppermint-like odour

Regulatory Status

Regulatory & Food Contact	Flavoring Agents Mint, Cool CIR / INCI: Cosmetics ingredient -> Buffering/pH Adjusting; Conditioning/Emollient; Flavor; Fragrance; Other (Specify)
GHS notification summary	0.3% (7 / 2060)

GHS Hazard Classification

GHS notification summary	0.3% (7 / 2060)
Reported hazard statements	H315 (97.6%), H319 (31.9%), H320, H336, H402

Documented Uses

• Painting (Solvents) [Category: Paint]
• Working with Glues and Adhesives [Category: Other]
• Using Disinfectants or Biocides [Category: Clean]
• Medication: topical antipruritic; medication (Vet): has been used as a mild local anesthetic, antiseptic & internally as a carminative & gastric sedative /Menthol/
• IN CHEWING GUM; CHEST RUBS /MENTHOL/
• AS AN INGREDIENT IN PREPARATIONS FOR THE NOSE & THROAT; IN OINTMENTS TO RELIEVE LOCAL IRRITATIONS OR FOR COUNTERIRRITANT PURPOSES; IN THROAT LOZENGES; ANTIPRURITIC /MENTHOL/

Synonyms

l-Menthol; (-)-menthol; 2216-51-5; Levomenthol; l-(-)-Menthol; (-)-Menthyl alcohol; Levomentholum; U.S.P. Menthol; (1R)-(-)-Menthol; (-)-(1R,3R,4S)-Menthol; D-(-)-Menthol; (-)-trans-p-Menthan-cis-ol; levomentol; (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol; Menthol, (1R,3R,4S)-(-)-; (1R,3R,4S)-(-)-MENTHOL

Frequently Asked Questions

What are the CAS number and molecular formula of L-MENTHOL?

CAS 2216-51-5; molecular formula C10H20O; molecular weight — g/mol.

What other names is L-MENTHOL known by?

l-Menthol, (-)-menthol, 2216-51-5, Levomenthol, l-(-)-Menthol, (-)-Menthyl alcohol.

What is the regulatory status of L-MENTHOL?

Documented regulatory listings: Flavoring Agents; Mint, Cool; CIR / INCI: Cosmetics ingredient -> Buffering/pH Adjusting; Conditioning/Emollient; Flavor; Fragrance; Other (Specify).

Is L-MENTHOL classified as hazardous?

0.3% of GHS notifications report no hazard classification (7 of 2060).

What are the key physical properties of L-MENTHOL?

Boiling Point: 421 °F at 760 mmHg (NTP, 1992); Boiling Point: 212; Boiling Point: 212 °C; Boiling Point: 212 °C ((-)-isomer 216.5).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.