Fidaxomicin

Description

Fidaxomicin · CAS 873857-62-6 · C52H74Cl2O18. UNII Z5N076G8YQ. Boiling Point: 1046.4.

Identification

CAS Registry Number	873857-62-6
PubChem CID	10034073
Molecular formula	C52H74Cl2O18
UNII (FDA)	Z5N076G8YQ

Computed Descriptors

Molecular Weight	1058.0
XLogP3	6.4
Hydrogen Bond Donor Count	7
Hydrogen Bond Acceptor Count	18
Rotatable Bond Count	15
Exact Mass	1056.4252209
Monoisotopic Mass	1056.4252209
Topological Polar Surface Area	267
Heavy Atom Count	72
Formal Charge	0

Physical & Chemical Properties

Boiling Point	1046.4

GHS Hazard Classification

Reported hazard statements	H302 (97.3%)

Documented Uses

• Fidaxomicin is indicated for the treatment of _Clostridioides_ (formerly _Clostridium_) _difficile_-associated diarrhea in adult and pediatric patients 6 months of age and older. Fidaxomicin should only be used in patients with proven or strongly suspected _C. difficile_ infection to reduce the risk of development of drug-resistant bacteria and maximize the therapeutic effectiveness of fidaxomicin and other antimicrobial agents.
• Fidaxomicin is a semisynthetic macrolide antibiotic used to treat Clostridium difficile-associated diarrhea in adults. Fidaxomicin has minimal systemic absorption and has not been linked to serum enzyme elevations during therapy or to instances of clinically apparent, acute liver injury.
• Breast Feeding; Lactation; Milk, Human; Anti-Infective Agents; Macrocyclic Antibiotics
• Fidaxomicin is an antibacterial prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of diarrhea caused by entericinfectionwith the bacteriumClostridioides difficile.
• Certain bacterial enteric infections can be opportunistic infections(OIs) of HIV.
• Take with or without food. High-fat meal decreases the Cmax of fidaxomicin and its metabolite in a clinically insignificant way.

Synonyms

Fidaxomicin; Tiacumicin B; 873857-62-6; Dificid; Dificlir; Lipiarmicin; OPT-80; fidaxomicine; Difimicin; PAR-101; Fidaxomicina; Lipiarmycin A3; Z5N076G8YQ; DTXSID901016415; OPT 80; PAR 101

Frequently Asked Questions

What are the CAS number and molecular formula of Fidaxomicin?

CAS 873857-62-6; molecular formula C52H74Cl2O18; molecular weight — g/mol.

What other names is Fidaxomicin known by?

Fidaxomicin, Tiacumicin B, 873857-62-6, Dificid, Dificlir, Lipiarmicin.

Is Fidaxomicin classified as hazardous?

Hazard statements reported: H302.

What are the key physical properties of Fidaxomicin?

Boiling Point: 1046.4.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.