镰刀菌酸

Description

Fusaric acid · CAS 536-69-6 · C10H13NO2. UNII JWJ963070N. Melting Point: 96-98 °C; LogP: 0.68.

Identification

CAS Registry Number	536-69-6
PubChem CID	3442
Molecular formula	C10H13NO2
IUPAC name	5-butylpyridine-2-carboxylic acid
UNII (FDA)	JWJ963070N

Computed Descriptors

Molecular Weight	179.22
XLogP3	2.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Exact Mass	179.094628657
Monoisotopic Mass	179.094628657
Topological Polar Surface Area	50.2
Heavy Atom Count	13
Formal Charge	0

Physical & Chemical Properties

Melting Point	96-98 °C
LogP	0.68

Physical description & handling notes

• COLORLESS CRYSTALS

GHS Hazard Classification

Reported hazard statements	H302 (98.6%)

Documented Uses

• Fusaric acid is a mycotoxin found in various Fusarium species such as Fusarium moniliforme. It has been proposed for a various therapeutic applications but is primarily used as a research tool. Fusaric acid can be found in contaminated corn and cereal grains including barley, wheat, millets and sorghum. (L1963, A3020)
• HARDEGGER, NIKLES, HELV CHIM ACTA 39, 505 (1956)...
• LARGE QUANTITIES OF FUSARIC ACID WERE PRODUCED BY FUSARIUM SPECIES GROWN ON A MODIFIED RICHARDS MEDIUM CONTAINING 2 MOLAR, BUT NOT 0.05 MOLAR GLUCOSE.
• ANTIBIOTIC (WILTING AGENT) FIRST ISOLATED FROM THE FUNGUS FUSARIUM HETEROSPORIUM, NEES: YABUTA ET AL, J AGR CHEM SOC JAPAN 10, 1059 (1934). ISOLATION FROM OTHER FUSARIUM SPECIES & FROM GIBBERELLA FUJIKUROI & SYNTHESIS: PLATTNER ET AL, HELV CHIM ACTA 37, 1379 (1954).
• 2-Pyridinecarboxylic acid, 5-butyl-: INACTIVE
• ADDITION OF EXCESSIVE AMOUNTS OF ZINC (30 MG/L) TO THE MEDIUM OF VIRULENT STRAIN OF FUSARIUM OXYSPORUM VASINFECTUM DECREASED THE CONTENT OF FUSARIC ACID BY 40% IN COMPARISON TO THAT IN THE SAME STRAIN GROWN ON MEDIUM WITH A NORMAL AMOUNT OF ZINC (0.2 MG/L). EXCESSIVE ZINC APPARENTLY ALTERS THE METABOLIC PATHWAY ASSOCIATED WITH FUSARIC ACID FORMATION & LEADS TO ACTIVATION OF THE DEHYDROGENASE SYSTEM. THE MAIN EFFECT OF EXCESSIVE ZINC APPEARS NOT TO BE LOSS OF VIABILITY BY PATHOGENIC FORMS, BUT LOSS OF VIRULENCE.

Synonyms

fusaric acid; 5-Butylpicolinic acid; 536-69-6; 5-Butylpyridine-2-carboxylic acid; Fusarinic acid; 5-Butyl-2-pyridinecarboxylic acid; 2-Pyridinecarboxylic acid, 5-butyl-; Picolinic acid, 5-butyl-; 5-n-Butylpyridine-2-carboxylic acid; DTXSID5023085; JWJ963070N; NSC-19870; DTXCID703085; Acid, Fusaric; Fusarate, Calcium; 5-Butyl-2-pyridinedicarboxylic Acid

Frequently Asked Questions

What are the CAS number and molecular formula of Fusaric acid?

CAS 536-69-6; molecular formula C10H13NO2; molecular weight — g/mol.

What other names is Fusaric acid known by?

fusaric acid, 5-Butylpicolinic acid, 536-69-6, 5-Butylpyridine-2-carboxylic acid, Fusarinic acid, 5-Butyl-2-pyridinecarboxylic acid.

Is Fusaric acid classified as hazardous?

Hazard statements reported: H302.

What are the key physical properties of Fusaric acid?

Melting Point: 96-98 °C; LogP: 0.68.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.