钆双酰胺

Description

Gadodiamide · CAS 131410-48-5 · C16H26GdN5O8. UNII 84F6U3J2R6.

Identification

CAS Registry Number	131410-48-5
PubChem CID	153921
Molecular formula	C16H26GdN5O8
IUPAC name	2-[bis[2-[carboxylatomethyl-[2-(methylamino)-2-oxoethyl]amino]ethyl]amino]acetate;gadolinium(3+)
UNII (FDA)	84F6U3J2R6

Computed Descriptors

Molecular Weight	573.66
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	11
Rotatable Bond Count	13
Exact Mass	574.10225
Monoisotopic Mass	574.10225
Topological Polar Surface Area	188
Heavy Atom Count	30
Formal Charge	0
Complexity	527

Physical description & handling notes

• Freely soluble in water
• Freely soluble in methanol; soluble in ethyl alcohol; slightly soluble in acetone, chloroform
• MW 1071.15. Osmolality (37 °C, 0.5 molarity): 789 mOsM/kg water. Viscosity (cP): 2.0 (20 °C), 1.4 (37 °C); density at 20 °C: 1.13; logP (butanol/water): -2.1 /Gadodiamide injection/
• Osmolality (37 °C, 1.0 molarity): 111 umol/kg water

GHS Hazard Classification

Reported hazard statements	H319 (100%)

Documented Uses

• For intravenous use in MRI to visualize lesions with abnormal vascularity (or those thought to cause abnormalities in the blood-brain barrier) in the brain (intracranial lesions), spine, and associated tissues
• Typical contrast agents are gadolinium-based compounds that possess a higher linear attenuation coefficient than soft tissues. /Contrast agents/
• Use (kg; approx.) in Germany (2009): >250
• Consumption (g per capita; approx.) in Germany (2009): 0.00305
• Consumption (g per capita) in the USA (2002): 0.00143
• Preparation: S. C. Quay, World Intellectual Property Organization (WIPO) patent 8602841 (1986 to New Salutar); idem, United States of America patent 4687659 (1987 to Salutar).

Synonyms

gadodiamide; 131410-48-5; GDDTPA-BMA; Gadodiamide anhydrous; Gadolinium-DTPA-BMA; Gd DTPA-BMA; S-041; 84F6U3J2R6; DTXSID201019701; HSDB 7547; DV 7572; CHEBI:37333; Gd-DTPA-BMA; RefChem:57217; Omniscan Unique Softpack; Gd-DTPA bis-(methylamide)

Frequently Asked Questions

What are the CAS number and molecular formula of Gadodiamide?

CAS 131410-48-5; molecular formula C16H26GdN5O8; molecular weight — g/mol.

What other names is Gadodiamide known by?

gadodiamide, 131410-48-5, GDDTPA-BMA, Gadodiamide anhydrous, Gadolinium-DTPA-BMA, Gd DTPA-BMA.

Is Gadodiamide classified as hazardous?

Hazard statements reported: H319.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.