GSK1120212 (DMSO solvate)

Name: GSK1120212 (DMSO solvate)
Brand: Jinan Shenghe Chemical Co., Ltd.

CAS 1187431-43-1C28H29FIN5O5SMW 693.5

GSK1120212 (DMSO solvate) (CAS No. 1187431-43-1) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Organic Chemicals. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number1187431-43-1

Molecular FormulaC28H29FIN5O5S

Molecular Weight693.5

Purity按批次COA提供(不公开发布)

Packaging按订单/批次确认(不公开发布)

ApplicationsOrganic Chemicals

CategoryOrganic Chemicals

Where it is used

Organic Chemicals

Packaging & Supply

Packaging按订单/批次确认(不公开发布)

Purity按批次COA提供(不公开发布)

StorageSealed, cool and dry place

Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of GSK1120212 (DMSO solvate)?

The CAS number of GSK1120212 (DMSO solvate) is 1187431-43-1.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of GSK1120212 (DMSO solvate)?

Main applications include Organic Chemicals.

How do I buy GSK1120212 (DMSO solvate) or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

GSK1120212 (DMSO solvate) · CAS 1187431-43-1 · C28H29FIN5O5S. UNII BSB9VJ5TUT.

Identification

CAS Registry Number	1187431-43-1
PubChem CID	50992434
Molecular formula	C28H29FIN5O5S
IUPAC name	N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide;methylsulfinylmethane
UNII (FDA)	BSB9VJ5TUT

Computed Descriptors

Molecular Weight	693.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	5
Exact Mass	693.09182
Monoisotopic Mass	693.09182
Topological Polar Surface Area	138
Heavy Atom Count	41
Formal Charge	0
Complexity	1120

GHS Hazard Classification

Reported hazard statements	H317 (100%), H361 (66.7%), H372 (100%), H400 (33.3%), H410 (100%)

H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]

H361 (66.7%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Documented Uses

Mekinist (Trametinib Dimethyl Sulfoxide)
Trametinib dimethyl sulfoxide is approved to be used alone or with dabrafenib mesylate to treat patients whose cancer has a certain mutation in the BRAF gene, including:
• Anaplastic thyroid cancer that has spread and cannot be treated with local therapy. It is used with dabrafenib mesylate.
• Glioma that is low grade in children aged 1 year and older who require systemic therapy. It is used with dabrafenib mesylate.
• With dabrafenib mesylate in patients who have had surgery to remove cancer that has spread to the lymph nodes.
• Alone or with dabrafenib mesylate in patients whose cancer cannot be removed by surgery or has spread to other parts of the body.

Synonyms

TRAMETINIB DIMETHYL SULFOXIDE; Trametinib DMSO; GSK1120212B; Mekinst; UNII-BSB9VJ5TUT; BSB9VJ5TUT; GSK-1120212B; CHEBI:75991; DTXSID30152223; RefChem:57976; DTXCID0074714; 1187431-43-1; Trametinib DMSO solvate; Trametinib (DMSO solvate); MFCD21609250; Trametinib dimethyl sulfoxide [USAN]

Frequently Asked Questions

What are the CAS number and molecular formula of GSK1120212 (DMSO solvate)?

CAS 1187431-43-1; molecular formula C28H29FIN5O5S; molecular weight — g/mol.

What other names is GSK1120212 (DMSO solvate) known by?

TRAMETINIB DIMETHYL SULFOXIDE, Trametinib DMSO, GSK1120212B, Mekinst, UNII-BSB9VJ5TUT, BSB9VJ5TUT.

Is GSK1120212 (DMSO solvate) classified as hazardous?

Hazard statements reported: H317, H361, H372, H400, H410.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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