hexamethonium chloride

Description

hexamethonium chloride · CAS 60-25-3 · C12H30Cl2N2. UNII TIV4Q933FU.

Identification

Computed Descriptors

Physical description & handling notes

• Liquid

Regulatory Status

GHS Hazard Classification

Documented Uses

• All Other Basic Organic Chemical Manufacturing
• 1,6-Hexanediaminium, N1,N1,N1,N6,N6,N6-hexamethyl-, chloride (1:2): ACTIVE
• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
• Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.
• Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses.

Synonyms

Hexamethonium chloride; 60-25-3; Hexamethonium dichloride; Hestrium chloride; DTXSID3044700; TIV4Q933FU; Hexamethylene(bistrimethylammonium)chloride; N,N,N,N',N',N'-hexamethylhexane-1,6-diaminium dichloride; DTXCID1024700; NSC-21643; 1,6-Hexanediaminium, N1,N1,N1,N6,N6,N6-hexamethyl-, chloride (1:2); NSC21643; Chloride, Hexamethonium; RefChem:146066; 200-465-1; Depressin

Frequently Asked Questions

What are the CAS number and molecular formula of hexamethonium chloride?

CAS 60-25-3; molecular formula C12H30Cl2N2; molecular weight — g/mol.

What other names is hexamethonium chloride known by?

Hexamethonium chloride, 60-25-3, Hexamethonium dichloride, Hestrium chloride, DTXSID3044700, TIV4Q933FU.

Is hexamethonium chloride classified as hazardous?

100% of GHS notifications report no hazard classification (104 of 104).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.