Isoflurane

Description

Isoflurane · CAS 26675-46-7 · C3H2ClF5O. UNII CYS9AKD70P. Boiling Point: 48.5; Boiling Point: 48.5 °C; Boiling Point: 49 °C.

Identification

CAS Registry Number	26675-46-7
PubChem CID	3763
Molecular formula	C3H2ClF5O
IUPAC name	2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane
UNII (FDA)	CYS9AKD70P

Computed Descriptors

Molecular Weight	184.49
XLogP3	2.1
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	2
Exact Mass	183.9714332
Monoisotopic Mass	183.9714332
Topological Polar Surface Area	9.2
Heavy Atom Count	10
Formal Charge	0

Physical & Chemical Properties

Boiling Point	48.5
Boiling Point	48.5 °C
Boiling Point	49 °C
Boiling Point	119.3 °F
Melting Point	48-48.5
Solubility	4470
Solubility	In water, 4.47X10+3 mg/L at 37 °C
Solubility	3.56e+00 g/L
Density	1.45
Vapor Pressure	330.0 [mmHg]

Physical description & handling notes

• Clear colorless liquid with a mild odor; [Merck Index] Musty ethereal odor; [Abbott Laboratories MSDS]
• Liquid
• COLOURLESS LIQUID.
• Colorless liquid
• Clear, colorless liquid
• Slight odor

Regulatory Status

GHS notification summary	2.9% (3 / 103)

GHS Hazard Classification

GHS notification summary	2.9% (3 / 103)
Reported hazard statements	H336 (93.2%), H373 (40.8%)

Documented Uses

• Used as a special solvent and as an inhalation anesthetic; [Merck Index] A stable, non-explosive inhalation anesthetic, relatively free from significant side effects. [ChemIDplus]
• Solvent and dispersant for fluorinated materials
• Use (kg) in Switzerland (2009): >750
• Use (kg; approx.) in Germany (2009): >10000
• Consumption (g per capita) in Switzerland (2009): 0.096
• Consumption (g per capita; approx.) in Germany (2009): 0.12

Synonyms

isoflurane; 26675-46-7; 1-Chloro-2,2,2-trifluoroethyl difluoromethyl ether; Forane; 2-Chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane; Forene; Aerrane; Isoflurano; Compound 469; IsoFlo; Isofluranum; Ethane, 2-chloro-2-(difluoromethoxy)-1,1,1-trifluoro-; Terrell; DTXSID3020752; CYS9AKD70P; COMPOUND-469

Frequently Asked Questions

What are the CAS number and molecular formula of Isoflurane?

CAS 26675-46-7; molecular formula C3H2ClF5O; molecular weight — g/mol.

What other names is Isoflurane known by?

isoflurane, 26675-46-7, 1-Chloro-2,2,2-trifluoroethyl difluoromethyl ether, Forane, 2-Chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane, Forene.

Is Isoflurane classified as hazardous?

2.9% of GHS notifications report no hazard classification (3 of 103).

What are the key physical properties of Isoflurane?

Boiling Point: 48.5; Boiling Point: 48.5 °C; Boiling Point: 49 °C; Boiling Point: 119.3 °F.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.