Indinavir

Description

Indinavir · CAS 150378-17-9 · C36H47N5O4. UNII 9MG78X43ZT. Melting Point: 167.5-168 °C; Melting Point: 167.5 - 168 °C; Solubility: 0.015.

Identification

CAS Registry Number	150378-17-9
PubChem CID	5362440
Molecular formula	C36H47N5O4
IUPAC name	(2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(pyridin-3-ylmethyl)piperazine-2-carboxamide
UNII (FDA)	9MG78X43ZT

Computed Descriptors

Molecular Weight	613.8
XLogP3	2.8
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	12
Exact Mass	613.36280500
Monoisotopic Mass	613.36280500
Topological Polar Surface Area	118
Heavy Atom Count	45
Formal Charge	0

Physical & Chemical Properties

Melting Point	167.5-168 °C
Melting Point	167.5 - 168 °C
Solubility	0.015
Solubility	4.82e-02 g/L
LogP	2.9
LogP	2.79

Physical description & handling notes

• Solid
• 262.9 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: APCI+; Dataset: TOXCAST; Source Identifier: DTXSID1044221]
• 262.3 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID1044221]
• 246.1 Ų [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID1044221]

GHS Hazard Classification

Reported hazard statements	H315 (100%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >100
• Consumption (g per capita; approx.) in Germany (2009): 0.00122
• Indinavir is an antiretroviral drug for the treatment of HIV infection.
• Indinavir is an antiretroviral protease inhibitor used in the therapy and prevention of human immunodeficiency virus (HIV) infection and the acquired immunodeficiency syndrome (AIDS). Indinavir can cause transient and usually asymptomatic elevations in serum aminotransferase levels and mild elevations in indirect bilirubin concentration. Indinavir is a rare cause of clinically apparent, acute liver injury. In HBV or HCV coinfected patients, antiretroviral therapy with indinavir may result in an exacerbation of the
• Breast Feeding; Lactation; Milk, Human; Anti-Infective Agents; Antiviral Agents; Anti-HIV Agents; Anti-Retroviral Agents; HIV Protease Inhibitors
• Avoid excessive or chronic alcohol consumption.

Synonyms

indinavir; 150378-17-9; Compound J; Indinavir anhydrous; 9MG78X43ZT; CHEBI:44032; DTXSID4043802; L 735,524; indinavirum; RefChem:790918; DTXCID2023802; J05AE02; L735 524; L 735 524; 180683-37-8; 5W6YA9PKKH

Frequently Asked Questions

What are the CAS number and molecular formula of Indinavir?

CAS 150378-17-9; molecular formula C36H47N5O4; molecular weight — g/mol.

What other names is Indinavir known by?

indinavir, 150378-17-9, Compound J, Indinavir anhydrous, 9MG78X43ZT, CHEBI:44032.

Is Indinavir classified as hazardous?

Hazard statements reported: H315.

What are the key physical properties of Indinavir?

Melting Point: 167.5-168 °C; Melting Point: 167.5 - 168 °C; Solubility: 0.015; Solubility: 4.82e-02 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.