isopropamide iodide

Description

isopropamide iodide · CAS 71-81-8 · C23H33N2O+. UNII 8B9I31H724. Melting Point: 182-184; Solubility: 4.24e-05 g/L.

Identification

CAS Registry Number	71-81-8
PubChem CID	3775
Molecular formula	C23H33N2O+
IUPAC name	(4-amino-4-oxo-3,3-diphenylbutyl)-methyl-di(propan-2-yl)azanium
UNII (FDA)	8B9I31H724

Computed Descriptors

Molecular Weight	353.5
XLogP3	4.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	8
Exact Mass	353.259288680
Monoisotopic Mass	353.259288680
Topological Polar Surface Area	43.1
Heavy Atom Count	26
Formal Charge	1

Physical & Chemical Properties

Melting Point	182-184
Solubility	4.24e-05 g/L

Physical description & handling notes

• Solid
• 185.74 Ų [M]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• Isopropamide is a long-acting quaternary anticholinergic drug. It is used in the treatment of peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility.

GHS Hazard Classification

Reported hazard statements	H302 (100%)

Documented Uses

• For the treatment of a wide range of gastrointestinal disorders, including such conditions as peptic ulcer, gastritis, hyperchlorhydria, functional diarrhea, irritable or spastic colon, pyloroduodenal irritability, pylorospasm, acute nonspecific gastroenteritis, biliary dyskinesia and chronic cholelithiasis, duodenitis, gastrointestinal spasm; it may also be used to treat genitourinary spasm.
• A - Alimentary tract and metabolism
• A03 - Drugs for functional gastrointestinal disorders
• A03A - Drugs for functional gastrointestinal disorders
• A03AB - Synthetic anticholinergics, quaternary ammonium compounds
• QA - Alimentary tract and metabolism

Synonyms

isopropamide; 7492-32-2; Isopropamid; Isopropamide ion; Isopropamide cation; (3-Carbamoyl-3,3-diphenylpropyl)diisopropylmethylammonium; DTXSID9023174; EINECS 231-316-9; 8B9I31H724; BRN 3913368; ISOPROPAMIDE [VANDF]; ISOPROPAMIDE [WHO-DD]; DTXCID203174; AMMONIUM, (3-CARBAMOYL-3,3-DIPHENYLPROPYL)DIISOPROPYLMETHYL-; Benzenepropanaminium, .gamma.-(aminocarbonyl)-N-methyl-N,N-bis(1-methylethyl)-.gamma.-phenyl-; Benzenepropanaminium, gamma-(aminocarbonyl)-N-methyl-N,N-bis(1-methylethyl)-gamma-phenyl-

Frequently Asked Questions

What are the CAS number and molecular formula of isopropamide iodide?

CAS 71-81-8; molecular formula C23H33N2O+; molecular weight — g/mol.

What other names is isopropamide iodide known by?

isopropamide, 7492-32-2, Isopropamid, Isopropamide ion, Isopropamide cation, (3-Carbamoyl-3,3-diphenylpropyl)diisopropylmethylammonium.

Is isopropamide iodide classified as hazardous?

Hazard statements reported: H302.

What are the key physical properties of isopropamide iodide?

Melting Point: 182-184; Solubility: 4.24e-05 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.