洛沙坦

Name: 洛沙坦
Brand: 济南圣和化工有限公司

CAS 114798-26-4C22H23ClN6OMW 422.9

洛沙坦，CAS 登记号 114798-26-4，由济南圣和化工有限公司现货供应，可提供纯度按批次COA提供(不公开发布) 的规格，下游主要用于有机化学品。支持样品与小批量试用，批量价格请联系我们获取，验收以批次 COA 为准。

规格参数

CAS号114798-26-4

分子式C22H23ClN6O

分子量422.9

熔点178-184

沸点682

LogP1.19

纯度按批次COA提供(不公开发布)

包装按订单/批次确认(不公开发布)

应用领域有机化学品

类别有机化学品

用途与场景

有机化学品

包装与供货

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

供货周期现货/按订单安排

文件与支持

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常见问题

在哪里能查到洛沙坦的 CAS 号？

本页已列出洛沙坦的 CAS 号：114798-26-4，可与随货 COA 核对。

可以提供哪些规格和包装？

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洛沙坦一般用在什么产品里？

主要涉及有机化学品。

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PubChem 公开数据

Description

Losartan · CAS 114798-26-4 · C22H23ClN6O. UNII JMS50MPO89. Boiling Point: 682; Melting Point: 178-184; Melting Point: 183.5-184.5 °C.

Identification

CAS Registry Number	114798-26-4
PubChem CID	3961
Molecular formula	C22H23ClN6O
IUPAC name	[2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
UNII (FDA)	JMS50MPO89

Computed Descriptors

Molecular Weight	422.9
XLogP3	4.3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	8
Exact Mass	422.1621871
Monoisotopic Mass	422.1621871
Topological Polar Surface Area	92.5
Heavy Atom Count	30
Formal Charge	0

Physical & Chemical Properties

Boiling Point	682
Melting Point	178-184
Melting Point	183.5-184.5 °C
Melting Point	183.5 - 184.5 °C
Solubility	<1mg/mL
Solubility	4.70e-03 g/L
LogP	1.19
LogP	6.1
LogP	2.53
Dissociation Constants	5.5

Physical description & handling notes

Solid
Light yellow solid
Stable under recommended storage conditions.
Hazardous decomposition products: Carbon oxides, nitrogen oxides (NOx), hydrogen chloride gas, potassium oxides.
201.6 Å² [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: APCI+; Dataset: TOXCAST; Source Identifier: DTXSID3044209]
204.9 Å² [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID3044209]

GHS Hazard Classification

Reported hazard statements	H315 (48.1%), H317 (48.1%), H319 (49.4%), H335 (48.1%), H360 (46.9%), H362 (46.9%), H413 (46.9%)

H315 (48.1%): Causes skin irritation [Warning Skin corrosion/irritation]

H317 (48.1%): May cause an allergic skin reaction [Warning Sensitization, Skin]

Documented Uses

Angiotensin II Type 1 Receptor Blockers; Anti-Arrhythmia Agents; Antihypertensive Agents
Use (kg; approx.) in Germany (2009): >5000
Consumption (g per capita; approx.) in Germany (2009): 0.0611
Consumption (g per capita) in the USA (2002): 0.0986
Pharmaceuticals -> Cardiovascular system -> Antihypertensions
Preparation: D. J. Carini, J. J. V. Duncia, European Patent Office patent 253310; D. J. Carini et al, United States of America patent 5138069 (1988, 1992 both to Du Pont).

Synonyms

losartan; 114798-26-4; allisartan; Angizaar; Losartic; Lozap; DUP-89; DTXSID7023227; [2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol; JMS50MPO89; NSC-758699; CHEBI:6541; HGP1405; HGP-1405; 2-Butyl-4-chloro-1-((2'-(1H-etrazol-5-yl) (1,1'-biphenyl)-4-yl)methyl)-1H-imidazole-5-methanol; DTXCID103227

Frequently Asked Questions

What are the CAS number and molecular formula of Losartan?

CAS 114798-26-4; molecular formula C22H23ClN6O; molecular weight — g/mol.

What other names is Losartan known by?

losartan, 114798-26-4, allisartan, Angizaar, Losartic, Lozap.

Is Losartan classified as hazardous?

Hazard statements reported: H315, H317, H319, H335, H360.

What are the key physical properties of Losartan?

Boiling Point: 682; Melting Point: 178-184; Melting Point: 183.5-184.5 °C; Melting Point: 183.5 - 184.5 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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