Lacidipine

Description

Lacidipine · CAS 103890-78-4 · C26H33NO6. UNII 260080034N. LogP: 4.43.

Identification

CAS Registry Number	103890-78-4
PubChem CID	5311217
Molecular formula	C26H33NO6
IUPAC name	diethyl 2,6-dimethyl-4-[2-[(E)-3-[(2-methylpropan-2-yl)oxy]-3-oxoprop-1-enyl]phenyl]-1,4-dihydropyridine-3,5-dicarboxylate
UNII (FDA)	260080034N

Computed Descriptors

Molecular Weight	455.5
XLogP3	4.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	11
Exact Mass	455.23078777
Monoisotopic Mass	455.23078777
Topological Polar Surface Area	90.9
Heavy Atom Count	33
Formal Charge	0

Physical & Chemical Properties

LogP	4.43

GHS Hazard Classification

Reported hazard statements	H302 (97.9%)

Documented Uses

• Indicated for the treatment of hypertension either alone or in combination with other antihypertensive agents, including β-adrenoceptor antagonists, diuretics, and ACE-inhibitors.
• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
• A class of drugs that act by selective inhibition of calcium influx through cellular membranes.
• C08C - Selective calcium channel blockers with mainly vascular effects
• C08CA - Dihydropyridine derivatives
• QC08 - Calcium channel blockers

Synonyms

Lacidipine; 103890-78-4; Lacipil; Motens; GR-43659X; Lacidipino; Lacidipinum; GR 43659X; Molap; DTXSID1046429; DTXCID9026429; 260080034N; RefChem:924456; C08CA09; LACIDIPINE [USAN]; MFCD00865936

Frequently Asked Questions

What are the CAS number and molecular formula of Lacidipine?

CAS 103890-78-4; molecular formula C26H33NO6; molecular weight — g/mol.

What other names is Lacidipine known by?

Lacidipine, 103890-78-4, Lacipil, Motens, GR-43659X, Lacidipino.

Is Lacidipine classified as hazardous?

Hazard statements reported: H302.

What are the key physical properties of Lacidipine?

LogP: 4.43.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.