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Description

Luliconazole · CAS 187164-19-8 · C14H9Cl2N3S2. UNII RE91AN4S8G.

Identification

CAS Registry Number	187164-19-8
PubChem CID	3003141
Molecular formula	C14H9Cl2N3S2
IUPAC name	(2E)-2-[(4R)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-ylacetonitrile
UNII (FDA)	RE91AN4S8G

Computed Descriptors

Molecular Weight	354.3
XLogP3	4
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	352.9614950
Monoisotopic Mass	352.9614950
Topological Polar Surface Area	92.2
Heavy Atom Count	21
Formal Charge	0

Physical description & handling notes

• Luliconazole kills the organisms Trichophyton rubrum and Epidermophyton floccosum, most likely by altering their fungal cell membranes.

GHS Hazard Classification

Reported hazard statements	H302 (66.7%), H315 (100%), H319 (100%), H335 (33.3%)

Documented Uses

• Luliconazole is indicated for the treatment of interdigital tinea pedis, tinea cruris, or tinea corporis infections caused by Trichophyton rubrum and Epidermophyton floccosum.
• Breast Feeding; Lactation; Antifungal Agents; Anti-Infective Agents
• Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.
• Established Pharmacologic Class [EPC] - Azole Antifungal
• Chemical Structure [CS] - Azoles
• Mechanisms of Action [MoA] - Cytochrome P450 2C19 Inhibitors

Synonyms

Luliconazole; 187164-19-8; Lulicon; NND-502; Luzu; PR-2699; NND502; (2E)-2-[(4R)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-ylacetonitrile; luliconazol; DTXSID3048607; RE91AN4S8G; (2E)-2-[(4R)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-yl-acetonitrile; DTXCID0028533; (-)-(E)-((4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)(1H-imidazol-1-yl)acetonitrile; (2E)-((4R)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene)(1H-imidazol-1-yl)acetonitrile; Lulifin

Frequently Asked Questions

What are the CAS number and molecular formula of Luliconazole?

CAS 187164-19-8; molecular formula C14H9Cl2N3S2; molecular weight — g/mol.

What other names is Luliconazole known by?

Luliconazole, 187164-19-8, Lulicon, NND-502, Luzu, PR-2699.

Is Luliconazole classified as hazardous?

Hazard statements reported: H302, H315, H319, H335.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.