利西拉来

Description

Lixisenatide · CAS 320367-13-3 · C215H347N61O65S. UNII 74O62BB01U.

Identification

CAS Registry Number	320367-13-3
PubChem CID	90472060
Molecular formula	C215H347N61O65S
UNII (FDA)	74O62BB01U

Computed Descriptors

Molecular Weight	4858
XLogP3	-30.8
Hydrogen Bond Donor Count	70
Hydrogen Bond Acceptor Count	77
Rotatable Bond Count	170
Exact Mass	4857.5510314
Monoisotopic Mass	4855.5443218
Topological Polar Surface Area	2090
Heavy Atom Count	342
Formal Charge	0

GHS Hazard Classification

Reported hazard statements	H318 (100%), H361 (100%)

Documented Uses

• Lixisenatide is indicated as an adjunct to diet and exercise to improve glycemic control in adult patients with type II diabetes mellitus. It is also available in combination with [insulin glargine] for the same indication.
• Lixisenatide is a recombinant DNA produced polypeptide analogue of human glucagon-like peptide-1 (GLP-1) which is used in combination with diet and exercise in the therapy of type 2 diabetes, either alone or in combination with other antidiabetic agents. Therapy with lixisenatide has not been associated with serum enzyme elevations or with episodes of clinically apparent liver injury.
• Breast Feeding; Lactation; Milk, Human; Hypoglycemic Agents; Incretins; Glucagon-Like Peptide-1 Agonists; GLP-1 Agonists
• Take at the same time every day.
• Take before a meal. Take lixisenatide within one hour before the first meal of the day.
• Established Pharmacologic Class [EPC] - GLP-1 Receptor Agonist

Synonyms

Lixisenatide; Adlyxin; Lyxumia; ZP10A peptide; 320367-13-3; ZP 10; AVE0010; AQVE-10010; AVE 0010; lixisenatida; lixisenatidum; AVE 010; AVE-010; ZP-10; AVE-0010; Des-38-proline-exendine-4 (Heloderma suspectum)-(1-39)-peptidylpenta-L-lysyl-L-lysinamide

Frequently Asked Questions

What are the CAS number and molecular formula of Lixisenatide?

CAS 320367-13-3; molecular formula C215H347N61O65S; molecular weight — g/mol.

What other names is Lixisenatide known by?

Lixisenatide, Adlyxin, Lyxumia, ZP10A peptide, 320367-13-3, ZP 10.

Is Lixisenatide classified as hazardous?

Hazard statements reported: H318, H361.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.