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Description

Latanoprostene bunod · CAS 860005-21-6 · C27H41NO8. UNII I6393O0922.

Identification

CAS Registry Number	860005-21-6
PubChem CID	11156438
Molecular formula	C27H41NO8
IUPAC name	4-nitrooxybutyl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate
UNII (FDA)	I6393O0922

Computed Descriptors

Molecular Weight	507.6
XLogP3	4.4
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	18
Exact Mass	507.28321727
Monoisotopic Mass	507.28321727
Topological Polar Surface Area	142
Heavy Atom Count	36
Formal Charge	0

Physical description & handling notes

• Upon applying an appropriate dose of latanoprost bunod, reduction in intraocular pressure begins approximately 1 to 3 hours later with a maximum intraocular pressure reduction effect demonstrated after 11 to 13 hours.

GHS Hazard Classification

Reported hazard statements	H242 (50%), H361 (50%)

Documented Uses

• Latanoprostene bunod opthalmic solution is indicated for the reduction of intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
• Breast Feeding; Lactation; Milk, Human; Antiglaucoma Agents; Prostaglandins
• S01E - Antiglaucoma preparations and miotics
• S01EE - Prostaglandin analogues
• QS01E - Antiglaucoma preparations and miotics
• QS01EE - Prostaglandin analogues

Synonyms

Latanoprostene BUNOD; 860005-21-6; Vyzulta; PF-3187207; NCX-116; Vesneo; latanoprosteno bunod; 4-nitrooxybutyl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate; I6393O0922; DTXSID101027765; 4-nitrooxybutyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5-enoate; latanoprostenum bunodum; RefChem:58122; DTXCID501513340; BOL-303259-X; NCX 116

Frequently Asked Questions

What are the CAS number and molecular formula of Latanoprostene bunod?

CAS 860005-21-6; molecular formula C27H41NO8; molecular weight — g/mol.

What other names is Latanoprostene bunod known by?

Latanoprostene BUNOD, 860005-21-6, Vyzulta, PF-3187207, NCX-116, Vesneo.

Is Latanoprostene bunod classified as hazardous?

Hazard statements reported: H242, H361.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.