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Lometrexol

CAS 106400-81-1C21H25N5O6MW 443.5

Lometrexol (CAS No. 106400-81-1) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Organic Chemicals. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number106400-81-1
Molecular FormulaC21H25N5O6
Molecular Weight443.5
LogP0.3
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsOrganic Chemicals
CategoryOrganic Chemicals

Where it is used

Organic Chemicals

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Lometrexol?

The CAS number of Lometrexol is 106400-81-1.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Lometrexol?

Main applications include Organic Chemicals.

How do I buy Lometrexol or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Lometrexol · CAS 106400-81-1 · C21H25N5O6. UNII 6P3AVY8A7Q.

Identification

CAS Registry Number106400-81-1
PubChem CID135413518
Molecular formulaC21H25N5O6
IUPAC name(2S)-2-[[4-[2-[(6R)-2-amino-4-oxo-5,6,7,8-tetrahydro-3H-pyrido[2,3-d]pyrimidin-6-yl]ethyl]benzoyl]amino]pentanedioic acid
UNII (FDA)6P3AVY8A7Q

Computed Descriptors

Molecular Weight443.5
XLogP30.3
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count8
Rotatable Bond Count9
Exact Mass443.18048353
Monoisotopic Mass443.18048353
Topological Polar Surface Area183
Heavy Atom Count32
Formal Charge0

GHS Hazard Classification

Reported hazard statementsH301 (100%)

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)

Documented Uses

  • Antimetabolites that are useful in cancer chemotherapy.
  • Inhibitors of the enzyme, dihydrofolate reductase (TETRAHYDROFOLATE DEHYDROGENASE), which converts dihydrofolate (FH2) to tetrahydrofolate (FH4). They are frequently used in cancer chemotherapy. (From AMA, Drug Evaluations Annual, 1994, p2033)

Synonyms

Lometrexol; 106400-81-1; Lometrexolum; 5,10-dideazatetrahydrofolic acid; 6P3AVY8A7Q; LY264618; 5,10-dideazatetrahydrofolate; L-Glutamic acid, N-(4-(2-((6R)-2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-d)pyrimidin-6-yl)ethyl)benzoyl)-; 5,10-Dideaza-5,6,7,8-tetrahydrofolic acid; NSC660025; 5,10-DDTF; RefChem:800022; (6R)-DDATHF; 6R-5,10-Dideazatetrahydrofolate; Pyrido(2,3-d)pyrimidine, L-glutamic acid derivative; DDATHF

Frequently Asked Questions

What are the CAS number and molecular formula of Lometrexol?

CAS 106400-81-1; molecular formula C21H25N5O6; molecular weight — g/mol.

What other names is Lometrexol known by?

Lometrexol, 106400-81-1, Lometrexolum, 5,10-dideazatetrahydrofolic acid, 6P3AVY8A7Q, LY264618.

Is Lometrexol classified as hazardous?

Hazard statements reported: H301.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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