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Mitoxantrone hydrochloride

CAS 70476-82-3C22H30Cl2N4O6MW 517.4

Mitoxantrone hydrochloride (CAS No. 70476-82-3) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Organic Chemicals. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number70476-82-3
Molecular FormulaC22H30Cl2N4O6
Molecular Weight517.4
Melting Point203-5 °C
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsOrganic Chemicals
CategoryOrganic Chemicals

Where it is used

Organic Chemicals

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Mitoxantrone hydrochloride?

The CAS number of Mitoxantrone hydrochloride is 70476-82-3.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Mitoxantrone hydrochloride?

Main applications include Organic Chemicals.

How do I buy Mitoxantrone hydrochloride or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Mitoxantrone hydrochloride · CAS 70476-82-3 · C22H30Cl2N4O6. UNII U6USW86RD0. Melting Point: 203-5 °C; Solubility: H2O 5- 10 (mg/mL); Solubility: 0.1NHCl 1 - 3 (mg/mL).

Identification

CAS Registry Number70476-82-3
PubChem CID51082
Molecular formulaC22H30Cl2N4O6
IUPAC name1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione;dihydrochloride
UNII (FDA)U6USW86RD0

Computed Descriptors

Molecular Weight517.4
Hydrogen Bond Donor Count10
Hydrogen Bond Acceptor Count10
Rotatable Bond Count12
Exact Mass516.1542401
Monoisotopic Mass516.1542401
Topological Polar Surface Area163
Heavy Atom Count34
Formal Charge0
Complexity571

Physical & Chemical Properties

Melting Point203-5 °C
SolubilityH2O 5- 10 (mg/mL)
Solubility0.1NHCl 1 - 3 (mg/mL)
Solubility10% Ethanol 3 - 5 (mg/mL)
Solubility95% Ethanol < 1 (mg/mL)
SolubilityMethanol < 1 (mg/mL)

Physical description & handling notes

  • Crystals; [Merck Index]
  • Blue-black solid from water ethanol
  • Sparingly soluble in water; slightly sol in methanol; practically insoluble in acetonitrile chloroform; acetone
  • pH 4 Acetate buffer 3 - 5 (mg/mL)
  • pH 9 Borate buffer < 1 (mg/mL)
  • 0.1 N NaOH decomposes (mg/mL)

GHS Hazard Classification

Reported hazard statementsH340 (92.9%), H360 (92.9%), H302, H310, H341, H351, H370, H372

H340 (92.9%): May cause genetic defects [Danger Germ cell mutagenicity]

H360 (92.9%): May damage fertility or the unborn child [Danger Reproductive toxicity]

Documented Uses

  • Used as an antineoplastic drug; [Merck Index]
  • DNA binding or cleaving agent used to treat acute nonlymphocytic leukemia, including myclogenous, promyclocytic, monocytic, and erythroid acute leukemias
  • /Mitoxantrone's/ range of antitumor activity is confined to leukemias, breast cancer, and prostate cancer. ... It also is used as a component of experimental high-dose chemotherapy regimens, with uncertain efficacy.
  • Consumption (g per capita) in the USA (2002): 2.34e-06
  • Mitoxantrone hydrochloride is approved to be used with other drugs to treat:
  • • Acute non-lymphocytic leukemia in adults.

Synonyms

70476-82-3; Mitoxantrone hydrochloride; Mitoxantrone dihydrochloride; CL-232315; Onkotrone; DTXSID0045173; Mitozantrone hydrochloride; CL 232,315; U6USW86RD0; NSC-301739; CL 232315; DTXCID8025173; CHEBI:50727; 1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthraquinone dihydrochloride; 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)-, dihydrochloride; 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthraquinone dihydrochloride

Frequently Asked Questions

What are the CAS number and molecular formula of Mitoxantrone hydrochloride?

CAS 70476-82-3; molecular formula C22H30Cl2N4O6; molecular weight — g/mol.

What other names is Mitoxantrone hydrochloride known by?

70476-82-3, Mitoxantrone hydrochloride, Mitoxantrone dihydrochloride, CL-232315, Onkotrone, DTXSID0045173.

Is Mitoxantrone hydrochloride classified as hazardous?

Hazard statements reported: H340, H360, H302, H310, H341.

What are the key physical properties of Mitoxantrone hydrochloride?

Melting Point: 203-5 °C; Solubility: H2O 5- 10 (mg/mL); Solubility: 0.1NHCl 1 - 3 (mg/mL); Solubility: 10% Ethanol 3 - 5 (mg/mL).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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