间氨基苯甲酰胺

Description

m-aminobenzamide · CAS 3544-24-9 · C7H8N2O. UNII 8J365YF1YH. Melting Point: 115-116 °C; LogP: log Kow = -0.33; LogP: -0.33.

Identification

CAS Registry Number	3544-24-9
PubChem CID	1645
Molecular formula	C7H8N2O
IUPAC name	3-aminobenzamide
UNII (FDA)	8J365YF1YH

Computed Descriptors

Molecular Weight	136.15
XLogP3	-0.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Exact Mass	136.063662883
Monoisotopic Mass	136.063662883
Topological Polar Surface Area	69.1
Heavy Atom Count	10
Formal Charge	0

Physical & Chemical Properties

Melting Point	115-116 °C
LogP	log Kow = -0.33
LogP	-0.33

Physical description & handling notes

• When heated to decomposition it emits toxic fumes of /Nitrogen oxide/.

GHS Hazard Classification

Reported hazard statements	H302 (87%), H315 (100%), H319 (100%), H335 (97.8%)

Documented Uses

• Poly(ADP-ribose) polymerase inhibitor, useful in treating ischemia-reperfusion injury.
• /EXPL THER/: Poly(ADP-ribose) polymerase (PARP) is a nuclear enzyme which plays an important role in regulating cell death and cellular responses to DNA repair. Pharmacological inhibitors of PARP are being considered as treatment for cancer both in monotherapy as well as in combination with chemotherapeutic agents and radiation, and were also reported to be protective against untoward effects exerted by certain anticancer drugs. ... pharmacological inhibition of PARP with 3-aminobenzamide or PJ-34 dose-dependently
• For more Therapeutic Uses (Complete) data for 3-AMINOBENZAMIDE (7 total), please visit the HSDB record page.
• Chemicals and drugs that inhibit the action of POLY(ADP-RIBOSE)POLYMERASES.
• Drugs used to potentiate the effectiveness of radiation therapy in destroying unwanted cells.
• Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.

Synonyms

3-aminobenzamide; 3544-24-9; m-Aminobenzamide; Benzamide, 3-amino-; Benzamide, m-amino-; meta-aminobenzamide; 8J365YF1YH; NSC-36962; CHEBI:64042; DTXSID90188922; RefChem:92958; DTXCID50111413; 222-586-9; 3-Amino-benzamide; 3-ABA; MFCD00007989

Frequently Asked Questions

What are the CAS number and molecular formula of m-aminobenzamide?

CAS 3544-24-9; molecular formula C7H8N2O; molecular weight — g/mol.

What other names is m-aminobenzamide known by?

3-aminobenzamide, 3544-24-9, m-Aminobenzamide, Benzamide, 3-amino-, Benzamide, m-amino-, meta-aminobenzamide.

Is m-aminobenzamide classified as hazardous?

Hazard statements reported: H302, H315, H319, H335.

What are the key physical properties of m-aminobenzamide?

Melting Point: 115-116 °C; LogP: log Kow = -0.33; LogP: -0.33.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.