氯化乙酰甲胆碱

Description

Methacholine chloride · CAS 62-51-1 · C8H18ClNO2. UNII 0W5ETF9M2K.

Identification

CAS Registry Number	62-51-1
PubChem CID	6114
Molecular formula	C8H18ClNO2
IUPAC name	2-acetyloxypropyl(trimethyl)azanium chloride
UNII (FDA)	0W5ETF9M2K

Computed Descriptors

Molecular Weight	195.69
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Exact Mass	195.1026065
Monoisotopic Mass	195.1026065
Topological Polar Surface Area	26.3
Heavy Atom Count	12
Formal Charge	0
Complexity	138

Physical description & handling notes

• >29.4 [ug/mL] (The mean of the results at pH 7.4)
• 134.8 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H302 (100%), H315 (100%), H319 (100%), H335 (98.2%)

Documented Uses

• 1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride (1:1): ACTIVE
• Agents causing contraction of the pupil of the eye. Some sources use the term miotics only for the parasympathomimetics but any drug used to induce miosis is included here.
• Drugs that mimic the effects of parasympathetic nervous system activity. Included here are drugs that directly stimulate muscarinic receptors and drugs that potentiate cholinergic activity, usually by slowing the breakdown of acetylcholine (CHOLINESTERASE INHIBITORS). Drugs that stimulate both sympathetic and parasympathetic postganglionic neurons (GANGLIONIC STIMULANTS) are not included here.
• Agents causing the narrowing of the lumen of a bronchus or bronchiole.
• Drugs that bind to and activate muscarinic cholinergic receptors (RECEPTORS, MUSCARINIC). Muscarinic agonists are most commonly used when it is desirable to increase smooth muscle tone, especially in the GI tract, urinary bladder and the eye. They may also be used to reduce heart rate.
• Cholinergic Receptor Agonist [EPC]; Cholinergic Agonists [MoA]

Synonyms

Methacholine chloride; 62-51-1; Provocholine; Amechol; Cloruro de metacolina; Chlorure de methacholine; Metacolina cloruro; 1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride; Methacholini chloridum; DTXSID7023271; 0W5ETF9M2K; Mecholine; Acetyl-2-methylcholine Chloride; NSC-757090; DTXCID203271; CHEBI:50142

Frequently Asked Questions

What are the CAS number and molecular formula of Methacholine chloride?

CAS 62-51-1; molecular formula C8H18ClNO2; molecular weight — g/mol.

What other names is Methacholine chloride known by?

Methacholine chloride, 62-51-1, Provocholine, Amechol, Cloruro de metacolina, Chlorure de methacholine.

Is Methacholine chloride classified as hazardous?

Hazard statements reported: H302, H315, H319, H335.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.