Nadifloxacin

Description

Nadifloxacin · CAS 124858-35-1 · C19H21FN2O4. UNII 6CL9Y5YZEQ. LogP: 1.89.

Identification

CAS Registry Number	124858-35-1
PubChem CID	4410
Molecular formula	C19H21FN2O4
IUPAC name	7-fluoro-8-(4-hydroxypiperidin-1-yl)-12-methyl-4-oxo-1-azatricyclo[7.3.1.05,13]trideca-2,5,7,9(13)-tetraene-3-carboxylic acid
UNII (FDA)	6CL9Y5YZEQ

Computed Descriptors

Molecular Weight	360.4
XLogP3	2.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	2
Exact Mass	360.14853532
Monoisotopic Mass	360.14853532
Topological Polar Surface Area	81.1
Heavy Atom Count	26
Formal Charge	0

Physical & Chemical Properties

LogP	1.89

Physical description & handling notes

• Nadifloxacin has anti-inflammatory properties. It attenuated the release of proinflammatory cytokines by human peripheral blood mononuclear cells and normal human keratinocytes.

GHS Hazard Classification

Reported hazard statements	H362 (100%), H373 (100%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >10
• Consumption (g per capita; approx.) in Germany (2009): 0.000122
• Substances that inhibit the growth or reproduction of BACTERIA.
• Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II.
• D10A - Anti-acne preparations for topical use
• D10AF - Antiinfectives for treatment of acne

Synonyms

nadifloxacin; 124858-35-1; jinofloxacin; Acuatim; OPC-7251; Nadifloxacine; Nadixa; Opc 7251; Nadifloxacino; Nadifloxacinum; NDFX; DTXSID5046483; 6CL9Y5YZEQ; NSC-759622; CHEBI:31889; DTXCID3026483

Frequently Asked Questions

What are the CAS number and molecular formula of Nadifloxacin?

CAS 124858-35-1; molecular formula C19H21FN2O4; molecular weight — g/mol.

What other names is Nadifloxacin known by?

nadifloxacin, 124858-35-1, jinofloxacin, Acuatim, OPC-7251, Nadifloxacine.

Is Nadifloxacin classified as hazardous?

Hazard statements reported: H362, H373.

What are the key physical properties of Nadifloxacin?

LogP: 1.89.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.