O-乙酰水杨酸

Description

O-Acetylsalicylic acid · CAS 98201-60-6 · C9H8O4. UNII R16CO5Y76E. Boiling Point: 140; Melting Point: 275 °F (NTP, 1992); Melting Point: 138-140.

Identification

CAS Registry Number	98201-60-6
PubChem CID	2244
Molecular formula	C9H8O4
IUPAC name	2-acetyloxybenzoic acid
UNII (FDA)	R16CO5Y76E

Computed Descriptors

Molecular Weight	180.16
XLogP3	1.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	180.04225873
Monoisotopic Mass	180.04225873
Topological Polar Surface Area	63.6
Heavy Atom Count	13
Formal Charge	0

Physical & Chemical Properties

Boiling Point	140
Melting Point	275 °F (NTP, 1992)
Melting Point	138-140
Melting Point	135 °C (rapid heating)
Melting Point	135 °C
Melting Point	275 °F
Flash Point	482 °F (NTP, 1992)
Solubility	10
Solubility	In water, 4,600 mg/L at 25 °C
Solubility	(77 °F): 0.3%

Physical description & handling notes

• Acetylsalicylic acid appears as odorless white crystals or crystalline powder with a slightly bitter taste. (NTP, 1992)
• Odorless, colorless to white, crystal-line powder. [aspirin] [Note: Develops the vinegar-like odor of acetic acid on contact with moisture.]
• Solid
• COLOURLESS-TO-WHITE CRYSTALS OR WHITE CRYSTALLINE POWDER WITH CHARACTERISTIC ODOUR.
• Odorless, colorless to white, crystal-line powder.
• Monoclinic tablets or needle-like crystals

Regulatory Status

GHS notification summary	0.3% (1 / 315)

GHS Hazard Classification

GHS notification summary	0.3% (1 / 315)
Reported hazard statements	H302 (95.6%), H315 (20.6%), H319 (22.2%), H335 (20%), H334, H412, H360, H370

Documented Uses

• Used in manufacturing and health care; [ACGIH TLVs and BEIs]
• Therapeutic Category: Analgesic; antipyretic; anti-inflammatory; antithrombotic.
• Therapeutic Category (Vet): Analgesic; antipyretic; anti-inflammatory; antithrombotic.
• CHEMICAL PROFILE: Virtually all aspirin is used in pharmaceutical products in aspirin tablets or in concert with other ingredients (1981)
• For more Uses (Complete) data for ACETYLSALICYLIC ACID (7 total), please visit the HSDB record page.
• Use (kg) in Switzerland (2009): >50000

Synonyms

aspirin; ACETYLSALICYLIC ACID; 50-78-2; 2-Acetoxybenzoic acid; 2-(Acetyloxy)benzoic acid; Acylpyrin; O-Acetylsalicylic acid; o-Acetoxybenzoic acid; Acenterine; Acetophen; Ecotrin; Salicylic acid acetate; Aceticyl; Acetosalin; Polopiryna; Aspirdrops

Frequently Asked Questions

What are the CAS number and molecular formula of O-Acetylsalicylic acid?

CAS 98201-60-6; molecular formula C9H8O4; molecular weight — g/mol.

What other names is O-Acetylsalicylic acid known by?

aspirin, ACETYLSALICYLIC ACID, 50-78-2, 2-Acetoxybenzoic acid, 2-(Acetyloxy)benzoic acid, Acylpyrin.

Is O-Acetylsalicylic acid classified as hazardous?

0.3% of GHS notifications report no hazard classification (1 of 315).

What are the key physical properties of O-Acetylsalicylic acid?

Boiling Point: 140; Melting Point: 275 °F (NTP, 1992); Melting Point: 138-140; Melting Point: 135 °C (rapid heating).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.