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Description

pancuronium bromide · CAS 15500-66-0 · C35H60Br2N2O4. UNII U9LY9Y75X2. Melting Point: 215 °C.

Identification

CAS Registry Number	15500-66-0
PubChem CID	27350
Molecular formula	C35H60Br2N2O4
IUPAC name	[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetyloxy-10,13-dimethyl-2,16-bis(1-methylpiperidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate dibromide
UNII (FDA)	U9LY9Y75X2

Computed Descriptors

Molecular Weight	732.7
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	6
Exact Mass	732.28993
Monoisotopic Mass	730.29198
Topological Polar Surface Area	52.6
Heavy Atom Count	43
Formal Charge	0
Complexity	1000

Physical & Chemical Properties

Melting Point	215 °C

Physical description & handling notes

• Crystals
• WHITE POWDER
• Odorless
• Bitter
• 1 g sol in 30 parts chloroform, 1 part water (20 °C)
• SOL IN ALCOHOL

GHS Hazard Classification

Reported hazard statements	H301 (100%), H311 (31.7%), H331 (31.7%)

Documented Uses

• Prepared by reaction of 2alpha, 3alpha: 16alpha, 17alpha-diepoxy- 17beta-acetoxy-5alpha-androstane with piperidine, and subsequent alkylation with methyl bromide.
• ... A precipitate may be formed if pancuronium bromide is mixed with barbiturates.
• Breast Feeding; Lactation; Muscle Relaxants; Neuromuscular Nondepolarizing Agents
• Neuromuscular Nondepolarizing Agents; Nicotinic Antagonists
• THE MAIN CLINICAL USE OF THE NEUROMUSCULAR BLOCKING AGENTS IS AS AN ADJUVANT IN SURGICAL ANESTHESIA TO OBTAIN RELAXATION OF SKELETAL MUSCLE, PARTICULARLY OF THE ABDOMINAL WALL ... MUSCLE RELAXATION IS ALSO OF VALUE IN VARIOUS ORTHOPEDIC PROCEDURES, SUCH AS THE CORRECTION OF DISLOCATIONS & THE ALIGNMENT OF FRACTURES. /NEUROMUSCULAR BLOCKING AGENTS/
• ...MAY BE USED MORE SAFELY IN PT WITH CARDIOVASCULAR DISEASE OR BRONCHIAL ASTHMA THAN ANY OTHER NEUROMUSCULAR BLOCKING DRUG. ...IT HAS ACTUALLY BEEN USED IN MGMNT OF STATUS ASTHMATICUS TO RELAX MUSCLES, THEREBY FACILITATING ARTIFICIAL RESPIRATION & DECR OXYGEN DEMAND. ... DURATION OF ACTION OF USUAL DOSE IS GENERALLY 30-60 MIN...

Synonyms

PANCURONIUM BROMIDE; 15500-66-0; Pancuronium dibromide; Mioblock; Bromuro de pancuronio; Bromure de pancuronium; Pancuronii bromidum; bromurex; ORG NA 97; ORG-NA 97; ORG-NA-97; U9LY9Y75X2; DTXSID9023415; NA 97; 3alpha,17beta-Diacetoxy-2beta,16beta-dipiperidino-5alpha-androstane dimethobromide; 2beta,16beta-Dipiperidino-5alpha-androstane-3alpha,17beta-diol diacetate dimethobromide

Frequently Asked Questions

What are the CAS number and molecular formula of pancuronium bromide?

CAS 15500-66-0; molecular formula C35H60Br2N2O4; molecular weight — g/mol.

What other names is pancuronium bromide known by?

PANCURONIUM BROMIDE, 15500-66-0, Pancuronium dibromide, Mioblock, Bromuro de pancuronio, Bromure de pancuronium.

Is pancuronium bromide classified as hazardous?

Hazard statements reported: H301, H311, H331.

What are the key physical properties of pancuronium bromide?

Melting Point: 215 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.