盐酸普鲁卡因酰胺

Description

procainamide hydrochloride · CAS 614-39-1 · C13H22ClN3O. UNII SI4064O0LX.

Identification

CAS Registry Number	614-39-1
PubChem CID	66068
Molecular formula	C13H22ClN3O
IUPAC name	4-amino-N-[2-(diethylamino)ethyl]benzamide;hydrochloride
UNII (FDA)	SI4064O0LX

Computed Descriptors

Molecular Weight	271.78
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	6
Exact Mass	271.1451400
Monoisotopic Mass	271.1451400
Topological Polar Surface Area	58.4
Heavy Atom Count	18
Formal Charge	0
Complexity	221

Physical description & handling notes

• >40.8 [ug/mL] (The mean of the results at pH 7.4)
• 155.8 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H302 (100%), H315 (93.6%), H319 (93.6%), H335 (93.6%)

Documented Uses

• Benzamide, 4-amino-N-[2-(diethylamino)ethyl]-, hydrochloride (1:1): ACTIVE
• Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
• A class of drugs that inhibit the activation of VOLTAGE-GATED SODIUM CHANNELS.

Synonyms

procainamide hydrochloride; 614-39-1; Procainamide Hcl; Procanbid; Procapan; Procan SR; Pronestyl-Sr; Amidoprocaine; Cardiorytmin; Benzamide, 4-amino-N-[2-(diethylamino)ethyl]-, monohydrochloride; Novocamid hydrochloride; DTXSID2049422; NSC-757279; SI4064O0LX; Procainamidi hydrochloridum; Benzamide, 4-amino-N-(2-(diethylamino)ethyl)-, monohydrochloride

Frequently Asked Questions

What are the CAS number and molecular formula of procainamide hydrochloride?

CAS 614-39-1; molecular formula C13H22ClN3O; molecular weight — g/mol.

What other names is procainamide hydrochloride known by?

procainamide hydrochloride, 614-39-1, Procainamide Hcl, Procanbid, Procapan, Procan SR.

Is procainamide hydrochloride classified as hazardous?

Hazard statements reported: H302, H315, H319, H335.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.