Pibrentasvir

Description

Pibrentasvir · CAS 1353900-92-1 · C57H65F5N10O8. UNII 2WU922TK3L. Solubility: <0.1 mg/mL.

Identification

CAS Registry Number	1353900-92-1
PubChem CID	58031952
Molecular formula	C57H65F5N10O8
UNII (FDA)	2WU922TK3L

Computed Descriptors

Molecular Weight	1113.2
XLogP3	7.4
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	17
Rotatable Bond Count	17
Exact Mass	1112.49069988
Monoisotopic Mass	1112.49069988
Topological Polar Surface Area	200
Heavy Atom Count	80
Formal Charge	0

Physical & Chemical Properties

Solubility	<0.1 mg/mL

GHS Hazard Classification

Reported hazard statements	H315 (100%), H319 (100%), H335 (100%), H413 (100%)

Documented Uses

• Indicated for the treatment of adult patients with acute and chronic hepatitis C virus (HCV) genotype 1, 2, 3, 4, 5 or 6 infection without cirrhosis or with compensated cirrhosis (Child-Pugh A). MAVYRET is also indicated for the treatment of adult patients with HCV genotype 1 infection, who previously have been treated with a regimen containing an HCV NS5A inhibitor or an NS3/4A protease inhibitor (PI), but not both.
• Breast Feeding; Lactation; Milk, Human; Antiviral Agents; NS5A Inhibitors
• Avoid St. John's Wort. Co-administration may lead to decreased serum concentrations of pibrentasvir.
• Established Pharmacologic Class [EPC] - Hepatitis C Virus NS5A Inhibitor
• Mechanisms of Action [MoA] - P-Glycoprotein Inhibitors
• Mechanisms of Action [MoA] - Breast Cancer Resistance Protein Inhibitors

Synonyms

Pibrentasvir; 1353900-92-1; ABT-530; A-1325912.0; 2WU922TK3L; DTXSID601027946; pibrentasvirum; RefChem:863096; DTXCID501513514; 829-351-5; Pibrentasvir [USAN]; ABT 530; Abt530; D10816; Pibrentasvir (ABT-530); C57H65F5N10O8

Frequently Asked Questions

What are the CAS number and molecular formula of Pibrentasvir?

CAS 1353900-92-1; molecular formula C57H65F5N10O8; molecular weight — g/mol.

What other names is Pibrentasvir known by?

Pibrentasvir, 1353900-92-1, ABT-530, A-1325912.0, 2WU922TK3L, DTXSID601027946.

Is Pibrentasvir classified as hazardous?

Hazard statements reported: H315, H319, H335, H413.

What are the key physical properties of Pibrentasvir?

Solubility: <0.1 mg/mL.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.