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Ponatinib hydrochloride

CAS 1114544-31-8C29H28ClF3N6OMW 569.0

Ponatinib hydrochloride (CAS No. 1114544-31-8) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Organic Chemicals. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number1114544-31-8
Molecular FormulaC29H28ClF3N6O
Molecular Weight569.0
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsOrganic Chemicals
CategoryOrganic Chemicals

Where it is used

Organic Chemicals

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Ponatinib hydrochloride?

The CAS number of Ponatinib hydrochloride is 1114544-31-8.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Ponatinib hydrochloride?

Main applications include Organic Chemicals.

How do I buy Ponatinib hydrochloride or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Ponatinib hydrochloride · CAS 1114544-31-8 · C29H28ClF3N6O. UNII 96R6PU3D8J.

Identification

CAS Registry Number1114544-31-8
PubChem CID46908927
Molecular formulaC29H28ClF3N6O
IUPAC name3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide;hydrochloride
UNII (FDA)96R6PU3D8J

Computed Descriptors

Molecular Weight569.0
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count6
Exact Mass568.1965217
Monoisotopic Mass568.1965217
Topological Polar Surface Area65.8
Heavy Atom Count40
Formal Charge0
Complexity910

GHS Hazard Classification

Reported hazard statementsH301 (100%), H302 (50%), H351 (50%), H360 (50%), H361 (50%), H372 (100%), H410 (50%)

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]

Documented Uses

  • Iclusig (Ponatinib Hydrochloride)
  • Ponatinib hydrochloride is approved for use in adults to treat:
  • • Acute lymphoblastic leukemia that is Philadelphia chromosomepositive. It is used:
  • • With chemotherapy in patients whose cancer is newly diagnosed.¹
  • • Alone in patients whose cancer has a T315I mutation or cannot be treated with other kinase inhibitors.
  • • Chronic myelogenous leukemia (CML). It is used:

Synonyms

Ponatinib hydrochloride; 1114544-31-8; Iclusig; AP 24534 hydrochloride; AP24534 HCL; 96R6PU3D8J; AP-24534 HCl; CHEBI:191940; DTXSID50149655; RefChem:58012; DTXCID0072146; Ponatinib HCl; Ponatinib Mono-hydrochloride; Ponatinib hydrochloride [USAN]; Ponatinib (HCl salt); Ponatinib (hydrochloride)

Frequently Asked Questions

What are the CAS number and molecular formula of Ponatinib hydrochloride?

CAS 1114544-31-8; molecular formula C29H28ClF3N6O; molecular weight — g/mol.

What other names is Ponatinib hydrochloride known by?

Ponatinib hydrochloride, 1114544-31-8, Iclusig, AP 24534 hydrochloride, AP24534 HCL, 96R6PU3D8J.

Is Ponatinib hydrochloride classified as hazardous?

Hazard statements reported: H301, H302, H351, H360, H361.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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