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Description

Rocuronium bromide · CAS 119302-91-9 · C32H53N2O4+. UNII WRE554RFEZ. Solubility: 2.84e-05 g/L.

Identification

CAS Registry Number	119302-91-9
PubChem CID	441290
Molecular formula	C32H53N2O4+
IUPAC name	[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3-hydroxy-10,13-dimethyl-2-morpholin-4-yl-16-(1-prop-2-enylpyrrolidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
UNII (FDA)	WRE554RFEZ

Computed Descriptors

Molecular Weight	529.8
XLogP3	5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	6
Exact Mass	529.40053318
Monoisotopic Mass	529.40053318
Topological Polar Surface Area	59
Heavy Atom Count	38
Formal Charge	1

Physical & Chemical Properties

Solubility	2.84e-05 g/L

Physical description & handling notes

• Solid
• Complete

Documented Uses

• For inpatients and outpatients as an adjunct to general anesthesia to facilitate both rapid sequence and routine tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
• Rocuronium is a non-depolarizing neuromuscular blocker widely used to produce muscle relaxation to help facilitate surgery and ventilation of the lungs in elective and emergent situations. Rocuonium is one of many non-depolarizing neuromuscular blockers available, but it has the advantage of being fast-acting and reversible.
• Breast Feeding; Lactation; Muscle Relaxants; Neuromuscular Nondepolarizing Agents
• Rocuronium (Class: Other Substances, Added Date: 03-2016)
• Drugs that interrupt transmission at the skeletal neuromuscular junction without causing depolarization of the motor end plate. They prevent acetylcholine from triggering muscle contraction and are used as muscle relaxants during electroshock treatments, in convulsive states, and as anesthesia adjuvants.
• Physiologic Effects [PE] - Neuromuscular Nondepolarizing Blockade

Synonyms

Rocuronium; 143558-00-3; Rocuronium ion; Rocuronium cation; WRE554RFEZ; CHEBI:8884; DTXSID6048339; Esmerone; RefChem:56463; DTXCID1028314; 1-(17-(acetoyl)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl)-1-(2-propenyl)pyrrolidinium; Zemuron; UNII-WRE554RFEZ; NCGC00167433-01; ROCURONIUM [MI]; Epitope ID:174837

Frequently Asked Questions

What are the CAS number and molecular formula of Rocuronium bromide?

CAS 119302-91-9; molecular formula C32H53N2O4+; molecular weight — g/mol.

What other names is Rocuronium bromide known by?

Rocuronium, 143558-00-3, Rocuronium ion, Rocuronium cation, WRE554RFEZ, CHEBI:8884.

What are the key physical properties of Rocuronium bromide?

Solubility: 2.84e-05 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.