苹果酸舒尼替尼

Description

Sunitinib malate · CAS 341031-54-7 · C26H33FN4O7. UNII LVX8N1UT73.

Identification

CAS Registry Number	341031-54-7
PubChem CID	6456015
Molecular formula	C26H33FN4O7
IUPAC name	N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide;(2S)-2-hydroxybutanedioic acid
UNII (FDA)	LVX8N1UT73

Computed Descriptors

Molecular Weight	532.6
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	10
Exact Mass	532.23332757
Monoisotopic Mass	532.23332757
Topological Polar Surface Area	172
Heavy Atom Count	38
Formal Charge	0
Complexity	765

GHS Hazard Classification

Reported hazard statements	H360 (93.8%), H372 (97.9%), H400 (12.5%), H410 (12.5%)

Documented Uses

• Sunitinib malate is approved to treat adults with:
• • Gastrointestinal stromal tumor. It is used in patients whose condition has become worse while taking imatinib mesylate or who are not able to take it.
• • Pancreatic neuroendocrine tumor. It is used in patients with progressive neuroendocrine tumors that cannot be removed by surgery or have spread.
• • Renal cell carcinoma (a type of kidney cancer). It is used:
• • in patients with advanced cancer
• • as adjuvant therapy in patients who have had a nephrectomy (surgery to remove the kidney) and have a high risk that the cancer will come back

Synonyms

Sunitinib malate; 341031-54-7; SU011248 L-malate salt; PHA-290940AD; sunitinib L-malate; SU010398; SU-011248 L-malate salt; DTXSID4046492; LVX8N1UT73; SU-010398; DTXCID801476195; NSC736511; RefChem:56081; Sutent; Sunitinib malate [USAN]; MFCD08282795

Frequently Asked Questions

What are the CAS number and molecular formula of Sunitinib malate?

CAS 341031-54-7; molecular formula C26H33FN4O7; molecular weight — g/mol.

What other names is Sunitinib malate known by?

Sunitinib malate, 341031-54-7, SU011248 L-malate salt, PHA-290940AD, sunitinib L-malate, SU010398.

Is Sunitinib malate classified as hazardous?

Hazard statements reported: H360, H372, H400, H410.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.