螺普利

Description

Spirapril · CAS 83647-97-6 · C22H30N2O5S2. UNII 96U2K78I3V. Solubility: 2.93e-02 g/L.

Identification

CAS Registry Number	83647-97-6
PubChem CID	5311447
Molecular formula	C22H30N2O5S2
IUPAC name	(8S)-7-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid
UNII (FDA)	96U2K78I3V

Computed Descriptors

Molecular Weight	466.6
XLogP3	0.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	10
Exact Mass	466.15961441
Monoisotopic Mass	466.15961441
Topological Polar Surface Area	147
Heavy Atom Count	31
Formal Charge	0

Physical & Chemical Properties

Solubility	2.93e-02 g/L

Physical description & handling notes

• Solid

Documented Uses

• Use (kg; approx.) in Germany (2009): >25
• Consumption (g per capita; approx.) in Germany (2009): 0.000305
• Spirapril is an ACE inhibitor class drug used to treat hypertension.
• Avoid hypertensive herbs (e.g. bayberry, blue cohosh, cayenne, ephedra, and licorice).
• Avoid potassium-containing products. Potassium products increase the risk of hyperkalemia.
• Limit salt intake. Salt may attenuate the antihypertensive effect.

Synonyms

Spirapril; 83647-97-6; Espirapril; Spiraprilum; 96U2K78I3V; DTXSID1044300; RefChem:184748; DTXCID9024300; C09AA11; Spirapril (INN); CHEMBL431; Spiraprilum [Latin]; Setrilan; Espirapril [Spanish]; SPIRAPRIL [INN]; Spirapril [INN:BAN]

Frequently Asked Questions

What are the CAS number and molecular formula of Spirapril?

CAS 83647-97-6; molecular formula C22H30N2O5S2; molecular weight — g/mol.

What other names is Spirapril known by?

Spirapril, 83647-97-6, Espirapril, Spiraprilum, 96U2K78I3V, DTXSID1044300.

What are the key physical properties of Spirapril?

Solubility: 2.93e-02 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.