triamcinolone

Description

triamcinolone · CAS 124-94-7 · C21H27FO6. UNII 1ZK20VI6TY. Melting Point: 270; Melting Point: 269-271 °C; Melting Point: 274 - 278 °C.

Identification

CAS Registry Number	124-94-7
PubChem CID	31307
Molecular formula	C21H27FO6
IUPAC name	(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
UNII (FDA)	1ZK20VI6TY

Computed Descriptors

Molecular Weight	394.4
XLogP3	1.2
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	2
Exact Mass	394.17916674
Monoisotopic Mass	394.17916674
Topological Polar Surface Area	115
Heavy Atom Count	28
Formal Charge	0

Physical & Chemical Properties

Melting Point	270
Melting Point	269-271 °C
Melting Point	274 - 278 °C
Solubility	In water, 80 mg/L at 25 °C
Solubility	8.47e-01 g/L
Vapor Pressure	7.20X10-15 mm Hg at 25 °C
LogP	log Kow = 1.16
LogP	0.2

Physical description & handling notes

• Solid
• Crystals
• FINE, WHITE OR PRACTICALLY WHITE, CRYSTALLINE POWDER; POLYMORPHIC
• FINE, WHITE OR SLIGHTLY OFF-WHITE CRYSTALS. SLIGHT, BITTER TASTE; SLIGHT ODOR; PRACTICALLY INSOL IN WATER. SOL IN CHLOROFORM; SLIGHTLY SOL IN ETHER; SPARINGLY SOL IN ALC & METHANOL. HYDRATED FORM MP 145-158 °C; ANHYDROUS FORM MP 170-185 °C /DIACETATE/
• WHITE TO CREAM-COLORED CRYSTALLINE POWDER. ODORLESS & TASTELESS TO SLIGHTLY BITTER TASTING; DECOMP @ ABOUT 295 °C. PRACTICALLY INSOL IN WATER; 1 G SOL IN 167 ML METHANOL, LESS THAN 20 ML CHLOROFORM. /HEXACETONIDE/
• WHITE TO CREAM-COLORED CRYSTALLINE POWDER. SLIGHT ODOR; PRACTICALLY INSOL IN WATER. VERY SOL IN DEHYDRATED ALC, CHLOROFORM, METHANOL; SLIGHTLY SOL IN ALC; SPARINGLY SOL IN ACETONE & ETHYL ACETATE /ACETONIDE/

GHS Hazard Classification

Reported hazard statements	H351 (63.3%), H361 (31.7%)

Documented Uses

• Glucocorticoid used for systemic or local anti-inflammatory activity
• Treatment of inflammation and related disorders in dogs and cats; and management and treatment of acute arthritis and allergic and dermatologic disorders in dogs and cats. Treatment of inflammation and related disorders in horses. /Acetonide; Vetalog Parenteral Veterinary/
• Topically: Use either ointment in cats for anti-inflammatory, antipruritic, antifungal, and antibacterial treatment of superficial bacterial infections, and for dermatologic disorders characterized by inflammation and dry or exudative dermatitis, particularly associated with bacterial or candidal (Candida albicans) infections. /Acetonide; Panolog Ointment/
• The drug is recommended ... for topical treatment of summer eczema. /Acetonide; Vetalog Cream/
• For more Uses (Complete) data for TRIAMCINOLONE (8 total), please visit the HSDB record page.
• Consumption (g per capita) in the USA (2002): 0.00815

Synonyms

triamcinolone; 124-94-7; Fluoxyprednisolone; Kenacort; Rodinolone; Volon; Triamcinolon; Delphicort; Ledercort; Tricortale; Celeste; Omcilon; Triamcinolona; Triamcinolonum; Fluoxiprednisolone; Tiamcinolonum

Frequently Asked Questions

What are the CAS number and molecular formula of triamcinolone?

CAS 124-94-7; molecular formula C21H27FO6; molecular weight — g/mol.

What other names is triamcinolone known by?

triamcinolone, 124-94-7, Fluoxyprednisolone, Kenacort, Rodinolone, Volon.

Is triamcinolone classified as hazardous?

Hazard statements reported: H351, H361.

What are the key physical properties of triamcinolone?

Melting Point: 270; Melting Point: 269-271 °C; Melting Point: 274 - 278 °C; Solubility: In water, 80 mg/L at 25 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.