trimipramine maleate

Description

trimipramine maleate · CAS 521-78-8 · C24H30N2O4. UNII 269K6498LD.

Identification

Computed Descriptors

Physical description & handling notes

• >61.6 [ug/mL] (The mean of the results at pH 7.4)
• 169.9 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Documented Uses

• For the treatment of depression and depression accompanied by anxiety, agitation or sleep disturbance
• Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
• Drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants (ANTIDEPRESSIVE AGENTS, TRICYCLIC) and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.

Synonyms

Trimipramine maleate; 521-78-8; Trimipramine hydrogen maleate; Stangyl; DTXSID2045315; NSC-758386; 269K6498LD; 5-(3-(Dimethylamino)-2-methylpropyl)-10,11-dihydro-5H-dibenz(b,f)azepine maleate (1:1); DTXCID0025315; Rhotrimine; 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-, (Z)-2-butenedioate (1:1); CHEBI:35030; 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-, (2Z)-2-butenedioate (1:1); Trimipramine Maleate (1:1); RefChem:56472; 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(dimethylamino)-2-methylpropyl)-, Maleate(1:1)

Frequently Asked Questions

What are the CAS number and molecular formula of trimipramine maleate?

CAS 521-78-8; molecular formula C24H30N2O4; molecular weight — g/mol.

What other names is trimipramine maleate known by?

Trimipramine maleate, 521-78-8, Trimipramine hydrogen maleate, Stangyl, DTXSID2045315, NSC-758386.

Is trimipramine maleate classified as hazardous?

Hazard statements reported: H302, H315, H319, H335, H361.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.