Tedizolid Phosphate

Description

Tedizolid Phosphate · CAS 856867-55-5 · C17H16FN6O6P. UNII O7DRJ6R4DW. LogP: 4.89.

Identification

CAS Registry Number	856867-55-5
PubChem CID	11476460
Molecular formula	C17H16FN6O6P
IUPAC name	[(5R)-3-[3-fluoro-4-[6-(2-methyltetrazol-5-yl)-3-pyridinyl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate
UNII (FDA)	O7DRJ6R4DW

Computed Descriptors

Molecular Weight	450.3
XLogP3	0.3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	11
Rotatable Bond Count	6
Exact Mass	450.08529741
Monoisotopic Mass	450.08529741
Topological Polar Surface Area	153
Heavy Atom Count	31
Formal Charge	0

Physical & Chemical Properties

LogP	4.89

GHS Hazard Classification

Reported hazard statements	H361 (97.2%), H373 (97.2%), H400 (97.2%), H410 (97.2%)

Documented Uses

• Tedizolid is indicated for the treatment of acute bacterial infections of the skin and skin structure (ABSSSI). To prevent drug resistance, tedizolid should only be used for infections that are caused by susceptible bacteria.
• Take at the same time every day.
• Substances that inhibit the growth or reproduction of BACTERIA.
• Oxazolidinone Antibacterial [EPC]; Breast Cancer Resistance Protein Inhibitors [MoA]; Oxazolidinones [CS]
• When given as a single oral dose, approximately 82% of tedizolid is excreted via the feces and 18% in urine. The majority is found as the inactive sulphate conjugate, with only 3% recovered unchanged. Over 85% of the elimination occurs within 96 hours.
• Tedizolid has an apparent oral clearance of 6.9 ± 1.7 L/hr for a single dose and 8.4 ± 2.1 L/hr at steady-state. The systemic clearance is 6.4 ± 1.2 L/hr for a single dose and 5.9 ± 1.4 L/hr at steady-state.

Synonyms

Tedizolid phosphate; 856867-55-5; Torezolid phosphate; Sivextro; TR-701 FA; TR-701FA; TR-701-FA; O7DRJ6R4DW; CHEBI:83326; DA7218; DTXSID30234977; RefChem:56098; DTXCID60157468; Tedizolid phosphate [USAN]; MFCD28098176; Tedizolid (phosphate)

Frequently Asked Questions

What are the CAS number and molecular formula of Tedizolid Phosphate?

CAS 856867-55-5; molecular formula C17H16FN6O6P; molecular weight — g/mol.

What other names is Tedizolid Phosphate known by?

Tedizolid phosphate, 856867-55-5, Torezolid phosphate, Sivextro, TR-701 FA, TR-701FA.

Is Tedizolid Phosphate classified as hazardous?

Hazard statements reported: H361, H373, H400, H410.

What are the key physical properties of Tedizolid Phosphate?

LogP: 4.89.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.