Troglitazone

Description

Troglitazone · CAS 97322-87-7 · C24H27NO5S. UNII I66ZZ0ZN0E. Melting Point: 184-186 °C; LogP: 3.6; LogP: 2.7.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• 193.9 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID8023719]

Documented Uses

• For the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise.
• Troglitazone was the first thiazolidinedione approved for use in the United States and was licensed for use in type 2 diabetes in 1997, but withdrawn 3 years later because of the frequency of liver injury including acute liver failure associated with its use.
• Substances which lower blood glucose levels.
• A - Alimentary tract and metabolism
• A10B - Blood glucose lowering drugs, excl. insulins
• QA - Alimentary tract and metabolism

Synonyms

troglitazone; 97322-87-7; Rezulin; Romglizone; Prelay; CS-045; Romozin; Noscal; troglitazona; troglitazonum; CI-991; DTXSID8023719; GR92132X; GR-92132X; 5-(4-(6-Hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)thiazolidine-2,4-dione; CHEBI:9753

Frequently Asked Questions

What are the CAS number and molecular formula of Troglitazone?

CAS 97322-87-7; molecular formula C24H27NO5S; molecular weight — g/mol.

What other names is Troglitazone known by?

troglitazone, 97322-87-7, Rezulin, Romglizone, Prelay, CS-045.

What are the key physical properties of Troglitazone?

Melting Point: 184-186 °C; LogP: 3.6; LogP: 2.7.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.