反苯环丙明

Description

tranylcypromine · CAS 155-09-9 · C9H11N. UNII 3E3V44J4Z9. Boiling Point: 79-80 °C @ 1.5-1.6 mm Hg; Melting Point: 79-80 °C at 1.50E+00 mm Hg; Melting Point: MP: 164-166 °C /Hydrochloride/.

Identification

CAS Registry Number	155-09-9
PubChem CID	5530
Molecular formula	C9H11N
IUPAC name	2-phenylcyclopropan-1-amine
UNII (FDA)	3E3V44J4Z9

Computed Descriptors

Molecular Weight	133.19
XLogP3	1.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	1
Exact Mass	133.089149355
Monoisotopic Mass	133.089149355
Topological Polar Surface Area	26
Heavy Atom Count	10
Formal Charge	0

Physical & Chemical Properties

Boiling Point	79-80 °C @ 1.5-1.6 mm Hg
Melting Point	79-80 °C at 1.50E+00 mm Hg
Melting Point	MP: 164-166 °C /Hydrochloride/
Solubility	48600
LogP	1.58
LogP	log Kow= 1.58 @ 25 °C
LogP	1.49

Physical description & handling notes

• Liquid
• Sol in water /Sulfate/
• Very slightly sol in alcohol, ether /Sulfate/
• Practically insol in chloroform /Sulfate/
• STABLE IN LIGHT, HEAT & IN AIR /SULFATE/
• 127.6 Ų [M+H]+ [CCS Type: TW; Method: Major Mix IMS/Tof Calibration Kit (Waters)]

GHS Hazard Classification

Reported hazard statements	H302 (100%), H315 (100%), H319 (100%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >25
• Consumption (g per capita; approx.) in Germany (2009): 0.000305
• Primarily indicated for the treatment of clinical depression. It is generally used to remedy various types of mood and anxiety disorders, typically after a last resort only after conventional antidepressants have been tried without success. It also has some off-label uses, such as in the treatment of post-traumatic stress disorder (PTSD). [Wikipedia]
• Burger, Yost, J Amer Chem Soc 70, 2198 (1948); Tedeschi, US patent 2,997,422 (1961 to SK & F).
• TRANYLCYPROMINE WAS WITHDRAWN FROM MARKET FOR SOME MONTHS DURING 1964, BUT AGAIN BECAME AVAIL FOR USE IN PT UNDER CLOSE MEDICAL OBSERVATION.
• For the treatment of major depressive episode without melancholia.

Synonyms

tranylcypromine; dl-Tranylcypromine; Transamine; Racemic Tranylcypromine; Jatrosom; Parnitene; SKF 385; Tranilcipromina; Tranylcyprominum; NSC80664; NSC-80664; Cyclopropanamine, 2-phenyl-, trans-(+-)-; Cyclopropylamine, 2-phenyl-, trans-(+-)-; DTXSID2023694; Tranylcypromin; trans 2 Phenylcyclopropylamine

Frequently Asked Questions

What are the CAS number and molecular formula of tranylcypromine?

CAS 155-09-9; molecular formula C9H11N; molecular weight — g/mol.

What other names is tranylcypromine known by?

tranylcypromine, dl-Tranylcypromine, Transamine, Racemic Tranylcypromine, Jatrosom, Parnitene.

Is tranylcypromine classified as hazardous?

Hazard statements reported: H302, H315, H319.

What are the key physical properties of tranylcypromine?

Boiling Point: 79-80 °C @ 1.5-1.6 mm Hg; Melting Point: 79-80 °C at 1.50E+00 mm Hg; Melting Point: MP: 164-166 °C /Hydrochloride/; Solubility: 48600.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.