四乙基乙酸铵四水合物

Description

tetraethylammonium acetate tetrahydrate · CAS 1185-59-7 · C8H20N+. UNII 5AV7G7EIEE. Melting Point: 360; Ionization Efficiency: 3.95; Ionization Efficiency: 2.7.

Identification

CAS Registry Number	1185-59-7
PubChem CID	5413
Molecular formula	C8H20N+
IUPAC name	tetraethylazanium
UNII (FDA)	5AV7G7EIEE

Computed Descriptors

Molecular Weight	130.25
XLogP3	1.7
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	0
Rotatable Bond Count	4
Exact Mass	130.159574642
Monoisotopic Mass	130.159574642
Topological Polar Surface Area	0
Heavy Atom Count	9
Formal Charge	1

Physical & Chemical Properties

Melting Point	360
Ionization Efficiency	3.95
Ionization Efficiency	2.7
Ionization Efficiency	MeCN (80%)
Ionization Efficiency	DOI:10.1021/ac902856t

Physical description & handling notes

• Soluble in water.
• Positive
• Agilent XCT
• Electrospray ionization
• formic acid (5.3nM)
• 125.7 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID9044457]

Documented Uses

• Tetraethylammonium is an experimental drug with no approved indication.
• A class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION POTENTIALS. They are used as ANTI-ARRHYTHMIA AGENTS and VASODILATOR AGENTS.
• Tetraethylammonium is eliminated by active renal tubular secretion by the cation transport system.
• Tetraethylammonium's mechanism of action is still being investigated, but it is known that it blocks autonomic ganglia, calcium- and voltage- activated potassium channels, and nicotinic acetylcholine receptors.

Synonyms

Tetraethylammonium; tetraethylazanium; Tetramon; N,N,N-Triethylethanaminium; Tetrylammonium; 66-40-0; TETRAETHYLAMMONIUM ION; AMMONIUM, TETRAETHYL-; Ethanaminium, N,N,N-triethyl-; 5AV7G7EIEE; Tetraethylammonium cation; NSC-156315; NSC-102778; DTXSID2045024; CHEBI:44296; Ion, Tetraethylammonium

Frequently Asked Questions

What are the CAS number and molecular formula of tetraethylammonium acetate tetrahydrate?

CAS 1185-59-7; molecular formula C8H20N+; molecular weight — g/mol.

What other names is tetraethylammonium acetate tetrahydrate known by?

Tetraethylammonium, tetraethylazanium, Tetramon, N,N,N-Triethylethanaminium, Tetrylammonium, 66-40-0.

What are the key physical properties of tetraethylammonium acetate tetrahydrate?

Melting Point: 360; Ionization Efficiency: 3.95; Ionization Efficiency: 2.7; Ionization Efficiency: MeCN (80%).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.