Tienilic acid

Description

Tienilic acid · CAS 40180-04-9 · C13H8Cl2O4S. UNII HC95205SY4. Melting Point: 149.

Identification

CAS Registry Number	40180-04-9
PubChem CID	38409
Molecular formula	C13H8Cl2O4S
IUPAC name	2-[2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy]acetic acid
UNII (FDA)	HC95205SY4

Computed Descriptors

Molecular Weight	331.2
XLogP3	4.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	5
Exact Mass	329.9520353
Monoisotopic Mass	329.9520353
Topological Polar Surface Area	91.8
Heavy Atom Count	20
Formal Charge	0

Physical & Chemical Properties

Melting Point	149

GHS Hazard Classification

Reported hazard statements	H302 (50%), H315 (50%), H319 (50%), H335 (100%)

Documented Uses

• For the treatment of hypertension.
• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
• Agents that promote the excretion of urine through their effects on kidney function.
• Gout suppressants that act directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma.
• C03CC - Aryloxyacetic acid derivatives
• QC03CC - Aryloxyacetic acid derivatives

Synonyms

Ticrynafen; Tienilic acid; 40180-04-9; Thienylic acid; 2-(2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy)acetic acid; Acido tienilico; Acide tienilique; Acidum tienilicum; 2-[2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy]acetic acid; DTXSID4023670; ANP 3624; (2,3-Dichloro-4-(2-thenoyl)phenoxy)acetic acid; 4-(2-Thienylketo)-2,3-dichlorophenoxyacetic acid; SKF 62698; [2,3-dichloro-4-(2-thienylcarbonyl)phenoxy]acetic acid; (2,3-Dichloro-4-(2-thiophenecarbonyl)phenoxy)acetic acid

Frequently Asked Questions

What are the CAS number and molecular formula of Tienilic acid?

CAS 40180-04-9; molecular formula C13H8Cl2O4S; molecular weight — g/mol.

What other names is Tienilic acid known by?

Ticrynafen, Tienilic acid, 40180-04-9, Thienylic acid, 2-(2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy)acetic acid, Acido tienilico.

Is Tienilic acid classified as hazardous?

Hazard statements reported: H302, H315, H319, H335.

What are the key physical properties of Tienilic acid?

Melting Point: 149.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.