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Tazemetostat hydrobromide

CAS 1467052-75-0C34H44N4O4MW 572.7

Tazemetostat hydrobromide (CAS No. 1467052-75-0) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Organic Chemicals. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number1467052-75-0
Molecular FormulaC34H44N4O4
Molecular Weight572.7
LogP2.82
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsOrganic Chemicals
CategoryOrganic Chemicals

Where it is used

Organic Chemicals

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Tazemetostat hydrobromide?

The CAS number of Tazemetostat hydrobromide is 1467052-75-0.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Tazemetostat hydrobromide?

Main applications include Organic Chemicals.

How do I buy Tazemetostat hydrobromide or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Tazemetostat hydrobromide · CAS 1467052-75-0 · C34H44N4O4. UNII Q40W93WPE1. LogP: 2.82.

Identification

CAS Registry Number1467052-75-0
PubChem CID66558664
Molecular formulaC34H44N4O4
IUPAC nameN-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-[ethyl(oxan-4-yl)amino]-2-methyl-5-[4-(morpholin-4-ylmethyl)phenyl]benzamide
UNII (FDA)Q40W93WPE1

Computed Descriptors

Molecular Weight572.7
XLogP34.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count9
Exact Mass572.33625590
Monoisotopic Mass572.33625590
Topological Polar Surface Area83.1
Heavy Atom Count42
Formal Charge0

Physical & Chemical Properties

LogP2.82

Physical description & handling notes

  • Tazemetostat is a methyltransferase inhibitor that prevents hyper-trimethylation of histones and inhibits cancer cell de-differentiation. The duration of action is long as it is given twice daily. Patients should be counselled regarding the risk of secondary malignancies and embryo-fetal toxicity.

Documented Uses

  • Tazemetostat is a methyltransferase inhibitor and antineoplastic agent used in the therapy of advanced epithelioid sarcoma. Tazemetostat is associated with a moderate rate of transient serum enzyme elevations during therapy, but has not been implicated in cases of clinically apparent acute liver injury with jaundice.
  • Established Pharmacologic Class [EPC] - Methyltransferase Inhibitor
  • Mechanisms of Action [MoA] - Methyltransferase Inhibitors
  • Mechanisms of Action [MoA] - Multidrug and Toxin Extrusion Transporter 1 Inhibitors
  • Tazemetostat is a Methyltransferase Inhibitor. The mechanism of action of tazemetostat is as a Methyltransferase Inhibitor, and Multidrug and Toxin Extrusion Transporter 1 Inhibitor, and Multidrug and Toxin Extrusion Transporter 2 K Inhibitor.
  • Methyltransferase Inhibitors [MoA]; Multidrug and Toxin Extrusion Transporter 1 Inhibitors [MoA]; Multidrug and Toxin Extrusion Transporter 2 K Inhibitors [MoA]; Methyltransferase Inhibitor [EPC]

Synonyms

Tazemetostat; 1403254-99-8; EPZ-6438; EPZ6438; E7438; Tazemetostatum; E-7438; Q40W93WPE1; DTXSID201025831; RefChem:56753; DTXCID601510082; EPZ 6438; Tazemetostat (EPZ-6438); Tazemetostat [INN]; MFCD24849415; Tazemetostat [USAN]

Frequently Asked Questions

What are the CAS number and molecular formula of Tazemetostat hydrobromide?

CAS 1467052-75-0; molecular formula C34H44N4O4; molecular weight — g/mol.

What other names is Tazemetostat hydrobromide known by?

Tazemetostat, 1403254-99-8, EPZ-6438, EPZ6438, E7438, Tazemetostatum.

What are the key physical properties of Tazemetostat hydrobromide?

LogP: 2.82.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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