5,5-Diphenylhydantoin

Description

5,5-Diphenylhydantoin · CAS 57-41-0 · C15H12N2O2. UNII 6158TKW0C5. Melting Point: 563 to 568 °F (NTP, 1992); Melting Point: 295; Melting Point: 295-298 °C.

Identification

CAS Registry Number	57-41-0
PubChem CID	1775
Molecular formula	C15H12N2O2
IUPAC name	5,5-diphenylimidazolidine-2,4-dione
UNII (FDA)	6158TKW0C5

Computed Descriptors

Molecular Weight	252.27
XLogP3	2.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	2
Exact Mass	252.089877630
Monoisotopic Mass	252.089877630
Topological Polar Surface Area	58.2
Heavy Atom Count	19
Formal Charge	0

Physical & Chemical Properties

Melting Point	563 to 568 °F (NTP, 1992)
Melting Point	295
Melting Point	295-298 °C
Melting Point	286 °C
Solubility	In water, 32 mg/L at 22 °C
Solubility	7.11e-02 g/L
LogP	2.47
LogP	log Kow = 2.47
LogP	2.2
LogP	2.21

Physical description & handling notes

• Phenytoin appears as fine white or almost white crystalline powder. Odorless or almost odorless. Tasteless. (NTP, 1992)
• Solid
• Needles (alcohol)
• White powder
• Odorless
• less than 0.1 mg/mL at 66 °F (NTP, 1992)

GHS Hazard Classification

Reported hazard statements	H302 (100%), H350 (31.9%), H351 (63.8%), H360 (95.7%), H402, H412, H340, H370

Documented Uses

• Antiepileptic drug useful in the treatment of epilepsy.
• THERAP CAT: Anticonvulsant; antiepileptic
• THERAP CAT (vet): Anticonvulsant
• Use (kg; approx.) in Germany (2009): >2500
• Consumption (g per capita; approx.) in Germany (2009): 0.0305
• Consumption (g per capita) in the USA (2002): 0.284

Synonyms

phenytoin; 5,5-DIPHENYLHYDANTOIN; 57-41-0; Diphenylhydantoin; 5,5-diphenylimidazolidine-2,4-dione; Phenytoine; Zentropil; Lepitoin; Diphantoin; Epamin; Dihydantoin; Dilabid; Sodanton; Dihycon; Diphenylan; Fenitoina

Frequently Asked Questions

What are the CAS number and molecular formula of 5,5-Diphenylhydantoin?

CAS 57-41-0; molecular formula C15H12N2O2; molecular weight — g/mol.

What other names is 5,5-Diphenylhydantoin known by?

phenytoin, 5,5-DIPHENYLHYDANTOIN, 57-41-0, Diphenylhydantoin, 5,5-diphenylimidazolidine-2,4-dione, Phenytoine.

Is 5,5-Diphenylhydantoin classified as hazardous?

Hazard statements reported: H302, H350, H351, H360, H402.

What are the key physical properties of 5,5-Diphenylhydantoin?

Melting Point: 563 to 568 °F (NTP, 1992); Melting Point: 295; Melting Point: 295-298 °C; Melting Point: 286 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.