2-氨基芴

Description

2-Aminofluorene · CAS 153-78-6 · C13H11N. UNII 3A69OS195N. Melting Point: 257 to 261 °F (NTP, 1992); Melting Point: 131-132 °C; Vapor Pressure: 0.0000279 [mmHg].

Identification

CAS Registry Number	153-78-6
PubChem CID	1539
Molecular formula	C13H11N
IUPAC name	9H-fluoren-2-amine
UNII (FDA)	3A69OS195N

Computed Descriptors

Molecular Weight	181.23
XLogP3	3.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Exact Mass	181.089149355
Monoisotopic Mass	181.089149355
Topological Polar Surface Area	26
Heavy Atom Count	14
Formal Charge	0

Physical & Chemical Properties

Melting Point	257 to 261 °F (NTP, 1992)
Melting Point	131-132 °C
Vapor Pressure	0.0000279 [mmHg]
LogP	3.14

Physical description & handling notes

• 2-aminofluorene is a brown crystal powder. (NTP, 1992)
• Brown solid; [CAMEO] Off-white powder; [MSDSonline]
• NEEDLES FROM DIL ALC
• LONG PLATES FROM DIL ALCOHOL
• less than 1 mg/mL at 67.1 °F (NTP, 1992)
• SOL IN ALCOHOL, ETHER

GHS Hazard Classification

Reported hazard statements	H302 (37.5%), H312 (25%), H315 (25%), H319 (25%), H332 (25%), H335 (25%), H341 (62.5%), H351 (75%)

Documented Uses

• Used as an experimental carcinogen for research; [HSDB]
• Formation from 2-nitrofluorene: Kuhn, Org Syn 13: 74 (1933).
• ... N-2-fluorenylacetamide was discovered to be a powerful carcinogen prior to the possible use of the parent 2-fluorenamine as an insecticide. ... in 1938 before DDT was known & when insect pests were controlled with difficulty, 2-fluorenamine was a potent & promising insecticide.
• Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.
• Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.
• N-HYDROXY METABOLITES ... /HAVE BEEN/ STRONGLY IMPLICATED AS PROXIMATE CARCINOGENIC DERIVATIVES OF AROMATIC AMINES & AMIDES. THUS, IN RAT & SOME OTHER SPECIES, N-HYDROXYAMIDES & THEIR CONJUGATES WERE DEMONSTRATED TO BE METABOLITES OF SOME AROMATIC AMINES & AMIDES, INCL 2-FLUORENAMINE ...

Synonyms

2-aminofluorene; 9H-Fluoren-2-amine; 153-78-6; 2-Fluorenamine; Aminofluoren; 2-Fluoreneamine; Fluoren-2-amine; 2-Fluorenylamine; 2-Fluroenylamine; DTXSID1049223; 3A69OS195N; NSC-12274; DTXCID3029079; RefChem:85382; 205-817-8; Fluorene, 2-amino-

Frequently Asked Questions

What are the CAS number and molecular formula of 2-Aminofluorene?

CAS 153-78-6; molecular formula C13H11N; molecular weight — g/mol.

What other names is 2-Aminofluorene known by?

2-aminofluorene, 9H-Fluoren-2-amine, 153-78-6, 2-Fluorenamine, Aminofluoren, 2-Fluoreneamine.

Is 2-Aminofluorene classified as hazardous?

Hazard statements reported: H302, H312, H315, H319, H332.

What are the key physical properties of 2-Aminofluorene?

Melting Point: 257 to 261 °F (NTP, 1992); Melting Point: 131-132 °C; Vapor Pressure: 0.0000279 [mmHg]; LogP: 3.14.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.