2-bromo-2-chloro-1,1,1-trifluoroethane

Description

2-bromo-2-chloro-1,1,1-trifluoroethane · CAS 151-67-7 · C2HBrClF3. UNII UQT9G45D1P. Boiling Point: 122.4 °F at 760 mmHg (NTP, 1992); Boiling Point: 50.2; Boiling Point: 50.2 °C.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• Halothane is a clear colorless highly volatile liquid with a sweet chloroform-like odor. Density 1.875 g / cm3. Boiling point 122.4 °F (50.2 °C). Noncombustible.
• Clear, colorless liquid with a sweetish, pleasant odor; inhalation anesthetic; [NIOSH]
• Liquid
• HIGHLY VOLATILE COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR.
• Clear, colorless liquid with a sweetish, pleasant odor.
• Clear, colorless liquid with a sweetish, pleasant odor. [inhalation anesthetic]

Regulatory Status

GHS Hazard Classification

Documented Uses

• For the induction and maintenance of general anesthesia
• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Bromination of 2-chloro-1,1,2-trifluoroethylene to form 1,2-dibromo-1-chloro-1,2,2-trifluoroethane, isomerization of the product with anhydrous aluminum chloride to 1,1-dibromo-1-chloro-2,2,2-trifluoroethane, and reduction of the latter with hydrogen (catalyzed by platinum); the antimony chloride-catalysed reaction of hydrogen fluoride with 1,2-dibromo-1,1,2-trichloroethane.
• Preparation from a mixture of F3CCH2Cl and FCCBrCl: Suckling, Raventos, US 2921098 (1960 to I.C.I.); by rearrangement of F2BrCCHFCl: Scherer, Kuhn, US 2959624 (1960 to Hoechst); from BrClCHCBrCl2: Chapman, McGinty, GB 805764 (1958 to I.C.I.); from Br2ClCCF3: McGinty, US 3082263 (1963 to I.C.I.)
• ... /The use of chlorofluorocarbons for aerosol sprays/ was prohibited in 1979 except for a few specialized items, because of their depleting effect on stratospheric ozone. /Chlorofluorocarbons/
• Halothane is a potent volatile halogenated anesthetic gas that has been linked to many cases of idiosyncratic acute liver injury that are frequently severe. The potential of halothane to cause hepatotoxicity and the greater safety of newer anesthetics has led to a decrease in its use, currently limited to special situations, particularly in children. Because halothane is relatively inexpensive it continues to be used in developing countries.

Synonyms

halothane; 151-67-7; 2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE; Fluothane; Narcotane; Narcotan; Rhodialothan; Anestan; Ftorotan; Fluorotane; Ftuorotan; Halothan; Narkotan; Fluktan; Halotan; Halsan

Frequently Asked Questions

What are the CAS number and molecular formula of 2-bromo-2-chloro-1,1,1-trifluoroethane?

CAS 151-67-7; molecular formula C2HBrClF3; molecular weight — g/mol.

What other names is 2-bromo-2-chloro-1,1,1-trifluoroethane known by?

halothane, 151-67-7, 2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE, Fluothane, Narcotane, Narcotan.

Is 2-bromo-2-chloro-1,1,1-trifluoroethane classified as hazardous?

6% of GHS notifications report no hazard classification (3 of 50).

What are the key physical properties of 2-bromo-2-chloro-1,1,1-trifluoroethane?

Boiling Point: 122.4 °F at 760 mmHg (NTP, 1992); Boiling Point: 50.2; Boiling Point: 50.2 °C; Boiling Point: 50 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.