2-Amino-3,8-Dimethylimidazo[4,5-f]quinoxaline

Description

2-Amino-3,8-Dimethylimidazo[4,5-f]quinoxaline · CAS 77500-04-0 · C11H11N5. UNII 5GYH6416ZG. Melting Point: 295 - 300 °C; Vapor Pressure: 0.00000002 [mmHg]; LogP: log Kow = 1.01.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• Yellow solid; [Toronto Research Chemicals MSDS]
• Solid
• When heated to decomposition it emits toxic fumes of /nitrogen oxides/.
• pKa1 = 1.43 (secondary amine); pKa2 = 5.23 (secondary amine)

GHS Hazard Classification

Documented Uses

• Strong mutagen found in broiled foods. [ChemIDplus] Naturally produced when meats are heated or cooked; Used as a research chemical; [HSDB]
• No known commercial use.[DHHS/National Toxicology Program; Eleventh Report on Carcinogens: 2-Amino-3,8-Diemethylimidazo
• MeIQx was prepared in 21% overall yield from 4-fluoro-o-phenylenediamine. The 3,7-dimethyl isomer may be obtained as a minor by-product. The [14]C-label was introduced in the last step through cyclization with [14]C-cyanogen bromide. An alternative synthesis of MeIQx from p-fluoroaniline avoided the separation of isomers but gave poorer yield.
• ... heterocyclic amine formed during heating or cooking and /is/ found in cooked meat and fish
• Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.
• Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.

Synonyms

MeIQx; 77500-04-0; 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline; 3,8-dimethyl-3H-imidazo[4,5-f]quinoxalin-2-amine; 8-Methyl-IQX; 8-MeIQX; 2-AMINO-3,8-DIMETHYLIMIDAZO(4,5-F)QUINOXALINE; Me-IQX; MeIQx cpd; 2-Amino-3,8-dimethyl-3H-imidazo(4,5-f)quinoxaline; 3,8-dimethylimidazo[4,5-f]quinoxalin-2-amine; 3,8-DiMeIQX; 3,8-Dimethyl-3H-imidazo(4,5-f)quinoxalin-2-amine; 5GYH6416ZG; DTXSID1020801; 3H-Imidazo(4,5-f)quinoxalin-2-amine, 3,8-dimethyl-

Frequently Asked Questions

What are the CAS number and molecular formula of 2-Amino-3,8-Dimethylimidazo[4,5-f]quinoxaline?

CAS 77500-04-0; molecular formula C11H11N5; molecular weight — g/mol.

What other names is 2-Amino-3,8-Dimethylimidazo[4,5-f]quinoxaline known by?

MeIQx, 77500-04-0, 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline, 3,8-dimethyl-3H-imidazo[4,5-f]quinoxalin-2-amine, 8-Methyl-IQX, 8-MeIQX.

Is 2-Amino-3,8-Dimethylimidazo[4,5-f]quinoxaline classified as hazardous?

Hazard statements reported: H351.

What are the key physical properties of 2-Amino-3,8-Dimethylimidazo[4,5-f]quinoxaline?

Melting Point: 295 - 300 °C; Vapor Pressure: 0.00000002 [mmHg]; LogP: log Kow = 1.01; LogP: 1.01.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.