2-氨基-3-甲基-3H-咪唑并[4,5-F]喹啉

Description

2-Amino-3-methyl-3H-imidazo[4,5-F]quinoline · CAS 76180-96-6 · C11H10N4. UNII 30GL3D3T0G. Melting Point: >300 °C; Melting Point: 300 °C; LogP: 1.47.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• 2-amino-3-methylimidazo(4,5-f)quinoline appears as light tan crystalline solid or tan powder. (NTP, 1992)
• Tan solid; [CAMEO] Light grey to tan powder; [MSDSonline]
• Solid
• Crystalline solid
• greater than 572 °F (NTP, 1992)
• Insoluble (NTP, 1992)

GHS Hazard Classification

Documented Uses

• Produced commercially in small quantities for research purposes; [HSDB] Mutagen found in broiled food; [ChemIDplus]
• IQ is produced commercially in small quantities for research purposes.
• Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.
• Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.
• The metabolism of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) was studied in the male rat using ... 14C and 3H at positions 2 and 5 of the molecule, respectively. Adult male Fischer 344 rats were administered [2-14C]IQ or [5-3H]IQ by oral gavage at ... 20 or 40 mg/kg bw. Rats were also given [2-14C]IQ in the diet at ... 300 ppm for 2 days and after administration of unlabelled IQ (300 ppm) in the diet for approximately 6.5 wk for an additional 2 days. In the initial 48 hr following oral administration of 20 or 40
• Mixed and pure cultures of human intestinal anaerobic bacteria metabolized IQ to IQ-7-one.

Synonyms

76180-96-6; 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine; 2-Amino-3-methyl-3H-imidazo[4,5-f]quinoline; 2-Amino-3-methylimidazo(4,5-f)quinoline; N3-IQ; 2-Amino-3-methylimidazo[4,5-f]quinoline; 3-Methyl-3H-imidazo(4,5-f)quinolin-2-amine; DTXSID4020745; 2-AMINO-3-METHYL-3H-IMIDAZO(4,5-F)QUINOLINE; 2-AMIQ; 2-Amino-3-methylimidazo(4,5-f)-quinoline; 3H-Imidazo(4,5-f)quinolin-2-amine, 3-methyl-; 30GL3D3T0G; DTXCID00745; 2-amino-3-methylimidazolo(4,5-f)quinoline; CHEBI:42725

Frequently Asked Questions

What are the CAS number and molecular formula of 2-Amino-3-methyl-3H-imidazo[4,5-F]quinoline?

CAS 76180-96-6; molecular formula C11H10N4; molecular weight — g/mol.

What other names is 2-Amino-3-methyl-3H-imidazo[4,5-F]quinoline known by?

76180-96-6, 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine, 2-Amino-3-methyl-3H-imidazo[4,5-f]quinoline, 2-Amino-3-methylimidazo(4,5-f)quinoline, N3-IQ, 2-Amino-3-methylimidazo[4,5-f]quinoline.

Is 2-Amino-3-methyl-3H-imidazo[4,5-F]quinoline classified as hazardous?

Hazard statements reported: H302, H312, H332, H315, H319.

What are the key physical properties of 2-Amino-3-methyl-3H-imidazo[4,5-F]quinoline?

Melting Point: >300 °C; Melting Point: 300 °C; LogP: 1.47.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.