3-propylxanthine

Description

3-propylxanthine · CAS 41078-02-8 · C8H10N4O2. UNII DT7DT5E518. Melting Point: 287-289 °C; Melting Point: 287 - 289 °C; Solubility: 1200.

Identification

CAS Registry Number	41078-02-8
PubChem CID	1676
Molecular formula	C8H10N4O2
IUPAC name	3-propyl-7H-purine-2,6-dione
UNII (FDA)	DT7DT5E518

Computed Descriptors

Molecular Weight	194.19
XLogP3	0.3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
Exact Mass	194.08037557
Monoisotopic Mass	194.08037557
Topological Polar Surface Area	78.1
Heavy Atom Count	14
Formal Charge	0

Physical & Chemical Properties

Melting Point	287-289 °C
Melting Point	287 - 289 °C
Solubility	1200
Solubility	5.68e+00 g/L
LogP	0.33
LogP	-0.2

Physical description & handling notes

• Solid
• >29.1 [ug/mL] (The mean of the results at pH 7.4)
• Enprofylline is a synthetic dimethylxanthine derivative structurally related to theophylline and caffeine. It antagonizes erythrocyte phosphodiesterase, increasing cAMP activity.

GHS Hazard Classification

Reported hazard statements	H302 (100%), H312 (97.5%), H332 (97.5%)

Documented Uses

• Used in the management of symptoms of asthma. Also used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
• Agents that cause an increase in the expansion of a bronchus or bronchial tubes.
• Drugs that are used to treat asthma.
• Compounds that selectively bind to and block the activation of ADENOSINE A2 RECEPTORS.
• Rapidly absorbed from the digestive tract
• Enprofylline inhibits erythrocyte phosphodiesterase, resulting in an increase in erythrocyte cAMP activity. Subsequently, the erythrocyte membrane becomes more resistant to deformity. Along with erythrocyte activity, enprofylline also decreases blood viscosity by reducing plasma fibrinogen concentrations and increasing fibrinolytic activity.

Synonyms

ENPROFYLLINE; 41078-02-8; 3-Propylxanthine; 3-n-Propylxanthine; Enprofilina; Enprofyllinum; 3,7-Dihydro-3-propyl-1H-purine-2,6-dione; 1H-Purine-2,6-dione, 3,7-dihydro-3-propyl-; D-4028; DTXSID9045186; 3-Propyl-3,7-dihydro-purine-2,6-dione; DT7DT5E518; 3-propyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione; D 4028; DTXCID7025186; CHEBI:126237

Frequently Asked Questions

What are the CAS number and molecular formula of 3-propylxanthine?

CAS 41078-02-8; molecular formula C8H10N4O2; molecular weight — g/mol.

What other names is 3-propylxanthine known by?

ENPROFYLLINE, 41078-02-8, 3-Propylxanthine, 3-n-Propylxanthine, Enprofilina, Enprofyllinum.

Is 3-propylxanthine classified as hazardous?

Hazard statements reported: H302, H312, H332.

What are the key physical properties of 3-propylxanthine?

Melting Point: 287-289 °C; Melting Point: 287 - 289 °C; Solubility: 1200; Solubility: 5.68e+00 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.