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Crospovidone

CAS 25249-54-1C6H9NOMW 111.14

Crospovidone (CAS 25249-54-1) — formula C6H9NO, molecular weight 111.14; category pharmaceutical intermediates and APIs.

Specifications

CAS Number25249-54-1
Molecular FormulaC6H9NO
Molecular Weight111.14
Melting Point13 °C
Boiling Point96 °C @ 14 mm Hg; 193 °C @ 400 mm Hg
LogP0.4
CategoryPharma Excipients

Purchase Profile

What this product is

Crospovidone is a pharmaceutical intermediate or API compound with CAS registry number 25249-54-1 and molecular formula C6H9NO (molecular weight 111.14), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.

Identification

CAS number: 25249-54-1

Its molecular formula C6H9NO comprises 6 C, 9 H, 1 N, 1 O atoms.

Also known as: Crospovidone

Category: pharmaceutical intermediates and APIs

Frequently Asked Questions

What is the CAS number of Crospovidone?

The CAS registry number of Crospovidone is 25249-54-1.

What is the molecular formula and molecular weight of Crospovidone?

Molecular formula C6H9NO, molecular weight 111.14.

What other names is Crospovidone known by?

It is also registered under: Crospovidone.

Which category does Crospovidone belong to?

Category: Pharma Excipients.

PubChem Public Data

Public-database records for Crospovidone (CAS 25249-54-1), reproduced here for independent cross-checking.

Safety classification and hazard statements

GHS notification summary0.1% (1 / 963)
Reported hazard statementsH302, H312, H318, H332, H335, H351, H373, H311

H302: Harmful if swallowed [Warning Acute toxicity, oral]

H312: Harmful in contact with skin [Warning Acute toxicity, dermal]

Regulatory listings

Regulatory & Food ContactFDA Substance added to food: PROCESSING AID, SURFACE-FINISHING AGENT
FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS
POLYVINYL POLYPYRROLIDONE
CIR / INCI: Antistatic; Film forming; Binding; Emulsion stabilizing; Hair fixing
GHS notification summary0.1% (1 / 963)

Physical description and handling notes

  • Liquid
  • Clear to light straw colored liquid; [HSDB]
  • COLOURLESS-TO-YELLOW LIQUID.
  • White powder.
  • Clear to light straw colored liquid
  • Soluble in water and many organic solvents

Reported physical properties

沸点96 °C @ 14 mm Hg; 193 °C @ 400 mm Hg
沸点at 1.3kPa: 90-93 °C
沸点194 °F
熔点13 °C
熔点57 °F
闪点95 °C
闪点100.5 °C (213 °F) open cup
闪点95 °C closed cup
闪点93 °C
闪点199.4 °F

How this substance is indexed

CAS Registry Number25249-54-1
PubChem CID6917
分子式C6H9NO
IUPAC 名称1-ethenylpyrrolidin-2-one
UNII(FDA)76H9G81541

Documented uses

  • Used as a monomer in the production of polyvinyl pyrrolidone; also used in the production of other polymers and organic chemicals; [ACGIH]
  • Using Disinfectants or Biocides [Category: Clean]
  • Plastic Composites Manufacturing [Category: Industry]
  • Used to manufacture water-soluble and insoluble forms of polyvinyl pyrrolidone for pharmaceutical and cosmetic industries and to make copolymers with other monomers intended for use in contact with food. ...Used in cast films adherent to glass, metals, plastics.
  • Solvent for resins, co-monomer for polymerization, binder in cosmetic and pharmaceutical preparations.
  • ...About 10-15% of the monomer is used in the pharmaceutical industry for the production of PVP-iodine complex used as a disinfectant. It is also used as a reactive solvent of UV-curable resins for the production of printing inks and paints as paper and textile auxiliaries, and as an additive in the cosmetics industry.

Names this substance appears under

88-12-0; N-VINYL-2-PYRROLIDONE; 1-Vinyl-2-pyrrolidone; 1-Vinyl-2-pyrrolidinone; Vinylpyrrolidone; 1-ethenylpyrrolidin-2-one; 2-Pyrrolidinone, 1-ethenyl-; Vinylbutyrolactam; Vinylpyrrolidinone; 1-Vinylpyrrolidinone; 1-Ethenyl-2-pyrrolidinone; DTXSID2021440; DTXCID101440; RefChem:1092137; 201-800-4; 1-vinylpyrrolidin-2-one

Computed molecular descriptors

分子量111.14
XLogP30.4
氢键供体数0
氢键受体数1
可旋转键数1
精确质量111.068413911
单同位素质量111.068413911
拓扑极性表面积20.3
重原子数8
形式电荷0

Database abstract

PVP-K30 · CAS 25249-54-1 · C6H9NO. UNII 76H9G81541. 沸点: 96 °C @ 14 mm Hg; 193 °C @ 400 mm Hg; 沸点: at 1.3kPa: 90-93 °C; 沸点: 194 °F.

Source: PubChem / Wikidata; the batch COA governs where values differ.

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