✉ info@591daili.com☎ +86-18553102138
📞 WhatsApp中文
591daili 济南圣和化工
Home › Product Catalog › Adefovir Dipivoxyl

Adefovir Dipivoxyl

CAS 142340-99-6C20H32N5O8PMW 501.5

Adefovir Dipivoxyl (CAS 142340-99-6) — formula C20H32N5O8P, molecular weight 501.5.

Specifications

CAS Number142340-99-6
Molecular FormulaC20H32N5O8P
Molecular Weight501.5
LogP1.91

Purchase Profile

What this product is

Adefovir Dipivoxyl is a chemical compound with CAS registry number 142340-99-6 and molecular formula C20H32N5O8P (molecular weight 501.5).

Identification

CAS number: 142340-99-6

Its molecular formula C20H32N5O8P comprises 20 C, 32 H, 5 N, 8 O, 1 P atoms.

Also known as: Adefovir Dipivoxyl

Frequently Asked Questions

What is the CAS number of Adefovir Dipivoxyl?

The CAS registry number of Adefovir Dipivoxyl is 142340-99-6.

What is the molecular formula and molecular weight of Adefovir Dipivoxyl?

Molecular formula C20H32N5O8P, molecular weight 501.5.

What other names is Adefovir Dipivoxyl known by?

It is also registered under: Adefovir Dipivoxyl.

PubChem Public Data

Public-database records for Adefovir Dipivoxyl (CAS 142340-99-6), reproduced here for independent cross-checking.

Safety classification and hazard statements

Reported hazard statementsH302 (100%), H312 (95.1%), H332 (97.6%), H311 (50%), H331 (50%)

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H312 (95.1%): Harmful in contact with skin [Warning Acute toxicity, dermal]

Physical description and handling notes

  • Solid
  • Adefovir dipivoxil a diester prodrug of adefovir. Adefovir is an acyclic nucleotide analog with activity against human hepatitis B virus (HBV). The concentration of adefovir that inhibited 50% of viral DNA synthesis (IC50) in vitro ranged from 0.2 to 2.5 μM in HBV transfected human hepatoma cell lines. The combination of adefovir with lamivudine showed additive anti-HBV activity.

Reported physical properties

溶解度19
溶解度6.33e-01 g/L
LogP1.91
LogP0.8
LogP2.48

How this substance is indexed

CAS Registry Number142340-99-6
PubChem CID60871
分子式C20H32N5O8P
IUPAC 名称[2-(6-aminopurin-9-yl)ethoxymethyl-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate
UNII（FDA）U6Q8Z01514

Documented uses

  • Take with or without food. The absorption is unaffected by food.
  • Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
  • Inhibitors of reverse transcriptase (RNA-DIRECTED DNA POLYMERASE), an enzyme that synthesizes DNA on an RNA template.
  • Nucleoside Analog [EXT]; Nucleoside Reverse Transcriptase Inhibitors [MoA]; Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]
  • J - Antiinfectives for systemic use
  • J05 - Antivirals for systemic use

Names this substance appears under

ADEFOVIR DIPIVOXIL; 142340-99-6; Hepsera; Adefovir pivoxil; GS-0840; GS 0840; DTXSID5046487; Adefovir di(pivaloyloxymethyl) ester; 9-(2-((Bis((pivaloyloxy)methoxy)phosphinyl)methoxy)ethyl)adenine; 9-(2-((-Bis((pivaloyloxy)methoxy)phosphinyl)methoxy)ethyl)adenine; (((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphinylidene)bis(oxymethylene) 2,2-dimethylpropanoate; U6Q8Z01514; DTXCID3026487; CHEBI:31175; adefovir depivoxil; RefChem:56260

Computed molecular descriptors

分子量501.5
XLogP31.8
氢键供体数1
氢键受体数12
可旋转键数15
精确质量501.19884999
单同位素质量501.19884999
拓扑极性表面积167
重原子数34
形式电荷0

Database abstract

Adefovir Dipivoxyl · CAS 142340-99-6 · C20H32N5O8P. UNII U6Q8Z01514. 溶解度: 19; 溶解度: 6.33e-01 g/L; LogP: 1.91.

Source: PubChem / Wikidata; the batch COA governs where values differ.

You may also need

AdefovirCAS 106941-25-7›
Adefovir Impurity 12CAS 20245-85-6›
Adefovir Impurity 30CAS —›

Get a quote for Adefovir Dipivoxyl

Supplier: Jinan Shenghe Chemical Co., Ltd. · Reply within one business day.

Email Inquiry WhatsApp
鲁ICP备19031700号-1